Case studies
Our case studies showcase our work within all phases of drug development. Each case clearly states the challenges and customer needs, and the services and solutions we provided.
![](https://pharmetheus.com/wp-content/uploads/2023/06/Crovalimab-concentration.png)
Crovalimab dose justification based on Phase 3 data in paroxysomal nocturnal hemoglobinurea patients
![](https://pharmetheus.com/wp-content/uploads/2023/06/ketamine-PKPD-modelschematic-1.png)
Assessment of the probability of a drug asset to exceed the target efficacy value in major depression disorder trials using literature data of ketamine and esketamine
![](https://pharmetheus.com/wp-content/uploads/2023/06/Estimated-monthly-patch-sizes.png)
Model-informed microarray patches design for anti-retroviral drugs to treat children with HIV
![](https://pharmetheus.com/wp-content/uploads/2024/06/Car-T-Cell-Illustration-Web.jpg)
Optimizing CAR-T cell exposure
In absence of clear dose-exposure relationships, there is a need to find other means to optimize CAR-T cell exposure.