Quantitative approaches to drug development
We provide consultancy services to help our clients reduce uncertainty in research and regulatory questions, increasing confidence in the development of new medicines that can improve patients’ lives. Science and Services
About
Pharmetheus reduces uncertainty in all phases of drug development.
News
Don’t miss the chance to attend the fourth annual Educational Pharmacometrics Summer Symposium (EPSS) on June 3, 2025 the Makedonia Palace Hotel, Thessaloniki, Greece. A free symposium including presentations from experts and professionals in the pharmacometrics field, accompanied by case examples presented by student attendees to help you get a wide overview of this exciting field. This fourth EPSS in…
This study, published in the special issue of MDPI Pharmaceutics: Advances in Pharmacokinetics and Drug Interactions, explored drug-drug interactions (DDIs) and food effects for Bevurogant (BI 730357), a competitive antagonist of the retinoic acid-related orphan receptor γ (RORγ), investigated as an oral treatment for plaque psoriasis. The publication was co-authored by Dr. Tobias Kanacher, Assoc. Prof Dr. Erik Sjögren, and…
This research focuses on leveraging quantitative modeling to support dose selection in oncology drug development, presenting development of an exposure-tumour growth inhibition (E-TGI) model to investigate the relationship between brigimadlin exposure and tumour shrinkage using data from a phase I clinical trial. The aim was to support the selection of the recommended phase II dose (RP2D) for brigimadlin, a potent…
How we work
Traceability, accountability, and independent quality control are of utmost importance to us, and embedded in our way of working.
Publications
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Model Informed Drug Development (MIDD) consulting services
A quantitative framework to support and inform development program strategies and decisions.
“Sharing with colleagues is why I love working here”
Sophie Peigné supports clients with expert and strategic advice in pharmacometrics as well as hands-on modeling analyses for compounds in all development phases.
History of Pharmetheus
Our journey is an exciting one. We began as a start-up that spinned off from Uppsala University. Today, we have grown into a global medium-sized company, adding value to drug development each day.