Quantitative approaches to drug development

We provide consultancy services to help our clients reduce uncertainty in research and regulatory questions, increasing confidence in the development of new medicines that can improve patients’ lives.

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23.09.2024
Bioavailability of a novel sustained-release pellet formulation of 5-flucytosine in healthy-fed participants for use in patients with cryptococcal meningitis

The publication focuses on a novel treatment for Cryptococcal meningoencephalitis (CM), a leading cause of death among people living with HIV in sub-Saharan Africa. Current treatment with 5-flucytosine (5-FC) poses significant challenges due to its short half-life and complicated dosing schedule, risking patient compliance.

04.09.2024
Pharmetheus passes 100 employees and moves to new office in central Uppsala

Pharmetheus AB is happy to announce two significant events, highlighting its capacity and future ambitions. The company has organically grown its team past 100 employees, and is relocating its headquarters to a sustainability flagship in central Uppsala, allowing for an easy commute for the employees and its global clients. CEO, Peter Milligan, reflects on the development: – When I joined…

27.06.2024
New publication: Full random effects models (FREM): A practical usage guide

The tutorial titled “Full Random Effects Models (FREM): A Practical Usage Guide” delves into the innovative FREM methodology, a robust complement to traditional covariate modeling techniques. We believe this tutorial is a valuable resource for researchers and practitioners in the field of pharmacometrics, offering insights into the application of FREM to improve learnings from the analyses of clinical trial data,…

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Model Informed Drug Development

A quantitative framework to support and inform development program strategies and decisions.

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“Sharing with colleagues is why I love working here”

Sophie Peigné supports clients with expert and strategic advice in pharmacometrics as well as hands-on modeling analyses for compounds in all development phases.

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History of Pharmetheus

Our journey is an exciting one. We began as a start-up that spinned off from Uppsala University. Today, we have grown into a global medium-sized company, adding value to drug development each day.

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