Quantitative approaches to drug development
We provide consultancy services to help our clients reduce uncertainty in research and regulatory questions, increasing confidence in the development of new medicines that can improve patients’ lives. Science and Services
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Pharmetheus reduces uncertainty in all phases of drug development.
News
Pharmacometrics, a relatively young discipline using model-based methods for drug development, plays a vital role in internal decision-making and health authority interactions. However, the demand for skilled pharmacometricians currently exceeds the supply provided by academic institutions. Elodie Plan and Mats Karlsson took part in a group of experts, assembled by Peter Bonate, to provide insights in a publication in the…
The prediction-corrected visual predictive check (pcVPC) is a commonly used model diagnostic, especially in the context of heterogeneous study designs or adaptive dosing. While useful, the transformation applied in prediction correction can result in plots that are unintuitive and difficult to interpret — even for experienced modelers.
Key discussions from the first Open OSP Community Conference, highlighting advances in open-source PBPK and QSP modeling. Topics include translation of in vitro data to clinical pharmacokinetics, modeling in special populations, and regulatory applications of model-informed drug development.
How we work
Traceability, accountability, and independent quality control are of utmost importance to us, and embedded in our way of working.
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Model Informed Drug Development (MIDD) consulting services
A quantitative framework to support and inform development program strategies and decisions.
“Sharing with colleagues is why I love working here”
Sophie Peigné supports clients with expert and strategic advice in pharmacometrics as well as hands-on modeling analyses for compounds in all development phases.
History of Pharmetheus
Our journey is an exciting one. We began as a start-up that spinned off from Uppsala University. Today, we have grown into a global medium-sized company, adding value to drug development each day.