Erik Sjögren, Assoc. Prof., Ph.D.

Principal Consultant & PBPK-QSP Platform Scientific Lead


  • Joined Pharmetheus in 2017, actively working in client projects
  • Expertise includes physiological based pharmacokinetic and biopharmaceutics modeling and simulation, clinical pharmacology, and pediatrics across therapeutic areas
  • Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform research and supervise Ph.D. students. Previously, he worked as Acting Senior Lecturer at Uppsala University, Sweden and Postdoctoral Researcher at AstraZeneca Mölndal, Sweden
  • M.Sc. in Pharmaceutical Sciences (2004), Ph.D. in Pharmaceutical Sciences (2010), Associate Professor in Biopharmaceutics (2016) from Uppsala University, Sweden
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Pharmetheus affiliated publications

Predicting disease effect on the pharmacokinetics (PK) of sustained and immediate release formulations by applying physiologically based pharmacokinetic (PBPK) modellingA platform for mechanistic modelling of subcutaneous administration with the effect of immunogenicity within the Open Systems Pharmacology frameworkPhysiologically based pharmacokinetic (PBPK) modelling of cabotegravir (CAB) to support design of microarray patches (MAPs) for the treatment of HIV positive childrenOpen Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical SciencesPhysiologically-based pharmacokinetic modelling of recombinant factor IX Fc fusion protein (rFIXFc) and recombinant FIX (rFIX) to characterize extravasation and binding to type IV collagenMechanistic modelling of bioavailability and local immunogenicity after subcutaneous administration within the Open Systems Pharmacology frameworkPhysiologically based pharmacokinetic (PBPK) modeling of the oral absorption of 5-flucytosine to support further development of a sustained-release formulation for the treatment of cryptococcal meningoencephalitisOverview of Authorized Drug Products for Subcutaneous Administration: Pharmaceutical, Therapeutic, and Physicochemical PropertiesPhysiological Based Pharmacokinetic and Biopharmaceutics Modelling of Subcutaneously Administered Compounds – An Overview of In Silico ModelsA Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished ChildrenLumenfantrine Exposure in Malnourished Children: PBPK Modeling Applied for Predictions and Dose Adjustments