Publications

03.04.25

Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference

JournalPBPK/PBBMPharmacometricsQSP

Pharmaceutics. 2025 Mar 1;17(3):314.

Dallmann A, Feick D, Balazki P, Benamara S, Burghaus R, Chenel M, Choi SL, Cordes H, Guimarães M, Hamadeh A, Ince I, Job KM, Kanacher T, Kovar A, Kuepfer L, Lippert J, Macente J, Nauwelaerts N, Niederalt C, Peters S, Proença S, Sato M, Schaller S, Schlender JF, Schneider A, Sjögren E, Solodenko J, Staab A, Vrenken P, Wendl T, de Witte WEA, Teutonico D.

10.03.25

Exposure‐tumour growth inhibition modelling of brigimadlin using phase I solid tumour data to support phase II dose selection

JournalMIDDOncologyPharmacometricsProgram strategies and efficiencies

Br J Clin Pharmacol. 2025 Mar.

Neldemo I, Gausi K, Sarr C, Friberg LE, Sailer R, Lahmar M, Jayadeva G, Pérez-Pitarch A, Schmid U, Busse D.

01.03.25

Assessing Drug–Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption

InflammationJournalPBPK/PBBMRegulatory interactions

Pharmaceutics 2025, 17(3), 314;

Kanacher T, Sjögren E, Korell J, Plan EL, Gómez-Mantilla JD, Ince I..

25.02.25

Model-informed drug development of flucytosine sustained release formulation in the treatment of cryptococcal meningitis: A case study using PBPK modeling

Infectious diseasesJournalMIDDPBPK/PBBMProgram strategies and efficienciesSpecial populations

CPT Pharmacometrics Syst Pharmacol. 2025 Feb 25.

Eriksson J, Sjögren E, Gillon JY, Caplain H, Goyal V, Satam V, Robinson S, Ribeiro I, Chenel M.

22.02.25

The impact of misspecified covariate models on inclusion and omission bias when using fixed effects and full random effects models

MethodologyPharmacometrics

J Pharmacokinet Pharmacodyn. 2025 Feb 22;52(2):18.

Nyberg J, Jonsson EN.

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Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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