MIDD Archives - Pharmetheus

Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

Physiologically based pharmacokinetic modelling to support the development of a sustained-release formulation for the treatment of cryptococcal meningoencephalitis: An MIDD case study

Phase 1 interim population PK/PD modeling and recommended phase 2 dose exploration for IMM-1-104: A novel concept oral deep cyclic inhibitor of MEK

A novel model for Platelets Dynamics: a pragmatic systems approach to characterize thrombocytopenia across multiple compounds and drug classes

A workflow for comparing drug candidates based on Probability of Pharmacological Success (PoPS)

A circular PK/PD/PK model explains the exposure of bulevirtide and bile salts in adult patients with Hepatitis D

Optimal design of a reduced sampling schedule for the characterization of prolactin dynamics in healthy male volunteers and its evaluation to the describe the pharmacodynamic effect of a prolactin antagonist in a single rising dose study

Model-informed early clinical development of BI-1808, a novel monoclonal antibody to tumor necrosis factor receptor 2

Concentration-QTcF Analysis of Quizartinib in Patients With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

Population Pharmacokinetics (PopPK) of Quizartinib and Its Active Metabolite AC886 in Patients (Pts) With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

An item response theory model with bounded integer subcomponents to describe the Mayo Clinic subscores in patients with ulcerative colitis

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