Workshop: Physiologically-based absorption modeling with the OSP Suite (PK-Sim, MoBi)
Do you want to increase your capabilities to support decision making in drug development with PBPK and absorption modeling? Join this satellite workshop in conjunction with PAGE on the 24th-25th of June, 2024.
Workshop overview
This workshop teaches you how to use and leverage the Open Systems Pharmacology (OSP) suite (also known as PK-Sim® and MoBi®) for modeling of absorption after different routes of administration utilizing the standardized and well-established whole body PBPK model provided in PK-Sim® and the open modeling possibilities in MoBi®.
Several relevant OSP techniques are highlighted,such as: Creating and leveraging PK-Sim structures, model establishment strategies, R-based processes, applying available absorption model implementations, and how to approach custom development via MoBi. The goal is to give participants (beginners to advanced users) a solid foundation to apply PK-Sim® and MoBi® in future projects.
Workshop learning objectives
The workshop is 2 days and covers:
- Learning the fundamentals in PK-Sim
- Learning the fundamentals in MoBi
- Setting up a PBPK model in PK-Sim for oral absorption
- How to approach subcutaneous, lung, dermal and ocular absorption modeling in MoBi
- Using WB-PBPK-absorption models to establish an IVIVR
- Informing bioavailability study design using virtual populations
- Addressing bioequivalence via virtual trials
- Strategies to use WB-PBPK-absorption models to evaluate an administration route switch
Workshop target audience
The target audience are scientists with a modeling background and a basic understanding of the overall drug development process. To participate in hands-on activities the attendees need to bring their laptop. Make sure to install the OSP Suite and R, including functional OSPsuite environment, on your laptops prior to the workshop (for instructions and software, please visit https://github.com/Open-Systems-Pharmacology/Suite/releases/tag/v11.2.)
Workshop tutors
- Additional tutors may be added depending on the number of participants
In addition to the ordinary program the Pharmetheus tutors would be happy to schedule shorter individual free speed-consulting sessions in association to this workshop to support the participants on related topics.
Workshop logistic details
Date: Monday 24th -Tuesday 25th June, 2024
Time: 09:00 – 17:00
Place: Ergife Palace Hotel & Conference Center
Registration Fee
Fee: Commercial/ Industry € 1200, Academia/ Government € 600, Students € 300.
All fees are excl. VAT.
The fee includes coffee breaks and lunch for both days.