Development of a Physiologically-Based Pharmacokinetic Model for Coproporphyrin I (CP-I) Using the Open Systems Pharmacology Software Suite (PK-Sim and MoBi) for assessment of OATP1B-based DDIs

This poster describes a Coproporphyrin (CP-I) PBPK-model, which can be used in the freely accessible Open Systems Pharmacology Suite (PK-Sim and MoBi) to assess potential drug-drug interaction of new therapeutic drugs via OATP1B.