MIDD – Pharmetheus

An item response theory model with bounded integer subcomponents to describe the Mayo Clinic subscores in patients with ulcerative colitis

Writing reports of modelling and simulation analysis: Our experience in the field of pharmacometrics

A disease model predicting placebo response and remission status of patients with ulcerative colitis using modified Mayo score

Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery

Model-informed drug development of autologous CAR-T cell therapy: Strategies to optimize CAR-T cell exposure leveraging cell kinetic/dynamic modeling

Model Informed Drug Development: Collaboration Through A Common Framework

Towards Industrialisation of Probability of Pharmacological Success (PoPS)

Application of tumor size modelling and simulations to support the dose selection of BI 907828 for a Phase II study

Optimizing infusion rates for N,N-dimethyltryptamine based on either a continuous variable model or a bounded integer model

Physiologically based pharmacokinetic (PBPK) modeling of the oral absorption of 5-flucytosine to support further development of a sustained-release formulation for the treatment of cryptococcal meningoencephalitis

Virtual patients, digital twins and causal disease models: Paving the ground for in silico clinical trials

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