Cases

Our case studies showcase our work within all phases of drug development. Each case clearly states the challenges and customer needs, and the services and solutions we provided.

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Cases 9 of 9

Advancing Cryptococcal Meningoencephalitis treatment with MIDD: Integrating PBPK-PBBM

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Disease effect prediction on PK in the context of a switch from an immediate release to a sustained release formulation.

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Food effect prediction and dose selection, using PBPK/PBBM, in the context of a switch from an immediate release to a sustained release formulation

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PBPK-informed selection of formulation prototype and dosage in the context of a sustained release formulation development

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PBPK-informed design of formulation prototype in the context of a sustained release formulation development

Car-T-Cell-Illustration-Web

Optimizing CAR-T cell exposure

Estimated-monthly-patch-sizes

Model-informed microarray patches design for anti-retroviral drugs to treat children with HIV

ketamine-PKPD-modelschematic-1

Assessment of the probability of a drug asset to exceed the target efficacy value in major depression disorder trials using literature data of ketamine and esketamine

Crovalimab-concentration

Crovalimab dose justification based on Phase 3 data in paroxysomal nocturnal hemoglobinurea patients

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