Sofia Friberg Hietala, Ph.D.
Principal Consultant, Client Operations Manager
Bio
- Joined Pharmetheus in 2015, actively working in client projects, and serving as Clients Operations Manager
- Expertise includes clinical pharmacology, trial design, and regulatory advice in therapeutic areas such as metabolic diseases, rheumatology, and infectious diseases
- Previously worked as Pharmacokinetics and Pharmacometrics Assessor at the Medical Products Agency, Sweden, where she made scientific assessment of marketing authorization applications, specifically ADME properties, drug-drug interactions, and special populations, as Senior Clinical Pharmacometrician at AstraZeneca R&D, Sweden, and as Pharmacist at the hospital pharmacy Apoteket SU/Sahlgrenska, Sweden.
- M.Sc. in Pharmacy (1999) from Uppsala University, Sweden, and Ph.D. in Pharmacology from Gothenburg University, Sweden.
Pharmetheus affiliated publications
Population pharmacokinetic analysis of an octreotide depot (CAM2029) in the treatment of acromegalyExposure-efficacy analysis of datopotamab deruxtecan (Dato-DXd), a TROP2-directed antibody-drug conjugate, in patients with advanced non-small cell lung cancerPopulation pharmacokinetic analysis of Datopotamab deruxtecan (Dato-DXd), a TROP2-targeting antibody-drug conjugateExposure–Response Analyses for the MET Inhibitor Tepotinib Including Patients in the Pivotal VISION Trial: Support for Dosage RecommendationsArtemether-Lumefantrine Dosing for Malaria Treatment in Young Children and Pregnant Women: A Pharmacokinetic-Pharmacodynamic Meta-AnalysisA Regulatory View on Dose Finding Studies and on the Value of Dose-Exposure-Response Analysis