Moriah Pellowe, Ph.D.

Consultant

Portrait-of-Moriah-Pellowe_Pharmetheus

Bio

  • Joined Pharmetheus in 2021, actively working in client projects
  • Expertise includes physiological based pharmacokinetic modeling (PBPK) and mathematical modeling in therapeutic areas such as oncology
  • Previously worked as Postdoctoral Fellow at the University of Waterloo, Canada, where she developed a mechanistic inhalation model for drug disposition and an R-package for virtual bioequivalence testing to inform clinical trial design supported by a grant from the FDA, and as Sessional Lecturer at the University of Waterloo, Canada
  • B.Sc. in Mathematics (2014) from Redeemer University, Canada, and Ph.D. in Applied Mathematics (2020) from the University of Waterloo, Canada
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Pharmetheus affiliated publications

Absorption, Bioavailability, and Immunogenicity after Subcutaneous Administration: Evaluation of a Subcutaneous Platform within the Open Systems Pharmacology frameworkPhysiologically based pharmacokinetic (PBPK) modelling of cabotegravir (CAB) to support design of microarray patches (MAPs) for the treatment of HIV positive childrenA platform for mechanistic modelling of subcutaneous administration with the effect of immunogenicity within the Open Systems Pharmacology frameworkDevelopment of a Physiologically-Based Pharmacokinetic Model for Coproporphyrin I (CP-I) Using the Open Systems Pharmacology Software Suite (PK-Sim and MoBi) for assessment of OATP1B-based DDIsMechanistic modelling of bioavailability and local immunogenicity after subcutaneous administration within the Open Systems Pharmacology framework