Publications Archive

21.01.25

Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria

HematologyJournalMIDDPharmacologyRare diseasesTrial design and analysis

Br J Clin Pharmacol. 2025 Jan 21.

Cosson V, Fu R, Kulasekararaj A, Nishimura J-I, Panse J, Röth A, Scheinberg P, Tong H, Yoon S-S, Beveridge L, Gotanda K, Jaminion F, Henrich A, Lundberg P, Shi D, Sreckovic S, Zhang Y, Zhang Z, Benkali K, Buatois S.

13.12.24

A tutorial on pharmacometric Markov models

JournalMethodologyPharmacometrics

CPT Pharmacometrics Syst Pharmacol. 2024;00:1–20.

Ooi QX, Plan EL, Bergstrand M.

20.11.24

Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

JournalMIDDOncologyPharmacometricsProgram strategies and efficiencies

Adv Drug Deliv Rev. 2024 Nov 20:115476. Online ahead of print.

Liu H, Ibrahim EIK, Centanni M, Sarr C, Venkatakrishnan K, Friberg LE..

12.11.24

Concentration-QTcF analysis of quizartinib in patients with newly diagnosed FLT3-internal-tandem-duplication-positive acute myeloid leukemia

JournalOncologyPharmacometricsRegulatory interactions

Clin Transl Sci. 2024;17:e70065.

Vaddady P, Smania G, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Zheng M.

12.11.24

Population pharmacokinetic analysis of quizartinib in patients with newly diagnosed FLT3-internal-tandem-duplication-positive acute myeloid leukemia

JournalOncologyPharmacometricsRegulatory interactions

Clin Transl Sci. 2024;17:e70074.

Vaddady P, Glatard A, Smania G, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Zheng M.

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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

Featured Publications

Full random effects models (FREM): A practical usage guide

Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

A tutorial on pharmacometric Markov models

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Publications 5 of 190

Featured Publications

Full random effects models (FREM): A practical usage guide

Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

A tutorial on pharmacometric Markov models

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Publications 5 of 190

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