Trial design and analysis Archives - Page 3 of 3 - Pharmetheus

Assessment of Expected Drug Exposure Relative Maximum Safety Limits in Early Phase Studies

Bridging Physiologically Based Pharmacokinetic (PBPK) and Population Pharmacokinetic (PopPK) Analyses in Paediatric Drug Development: A Case Study Based on Intravenous Esomeprazole

Exposure-Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction

Dosing and Switching Strategies for Paliperidone Palmitate 3-Month Formulation in Patients with Schizophrenia Based on Population Pharmacokinetic Modeling and Simulation, and Clinical Trial Data

Pharmacokinetic and Exposure-Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients with Prior Myocardial Infarction (PEGASUS-TIMI 54)

Development of a Population Pharmacokinetic Model of Prucalopride in Children with Functional Constipation

Modelling and Simulation of Neurological Endpoints (Modified Rankin Scale [mRS] and National Institute of Health Stroke Scale [NIHSS]) to Aid Clinical Trial Design in Intracerebral Hemorrhage (ICH)

Contrast Enhancement in Bladder Tumors Examined with CT Urography Using Traditional Scan Phases

Pharmetheus-Pattern-196

A Bolus and Bolus Followed by Infusion Study of AZD3043, an Investigational Intravenous Drug for Sedation and Anesthesia: Safety and Pharmacodynamics in Healthy Male and Female Volunteers

Characterizing Variability in Warfarin Dose Requirements in Children Using Modelling and Simulation

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