Special considerations Archives - Pharmetheus

A Physiologically Based Pharmacokinetic Model of Atorvastatin Acid Predicting CYP3A4 and OATP1B Drug–Drug Interactions

Development of a PBPK model to predict monoclonal antibody pharmacokinetics and bioavailability following subcutaneous administration

Efficient and relevant stepwise covariate model building for pharmacometrics [2]

Predicting Reductions in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations from FEV1 – A Model-Based Meta-Analysis of Literature Data from Controlled Randomized Clinical Trials

Translating Pharmacometrics to a Pharmacoeconomic Model of COPD

Pharmetheus-Pattern-184

Model Informed Drug Development: Collaboration Through A Common Framework

Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

Application relevant shrinkage metrics

Use of informative prior distributions from mepolizumab data to support depemokimab PKPD model analysis

Pharmetheus-Pattern-208

Training the next generation of pharmacometric modelers: a multisector perspective

Virtual patients, digital twins and causal disease models: Paving the ground for in silico clinical trials

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