Oncology – Pharmetheus

Population pharmacokinetic analysis of Datopotamab deruxtecan (Dato-DXd), a TROP2-targeting antibody-drug conjugate.

Model-informed early clinical development of BI-1808, a novel monoclonal antibody to tumor necrosis factor receptor 2

Concentration-QTcF Analysis of Quizartinib in Patients With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

Population Pharmacokinetics (PopPK) of Quizartinib and Its Active Metabolite AC886 in Patients (Pts) With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

Rituximab PK and PD evaluation based on a study in diffuse large B-cell lymphoma: influence of tumor size on PK and assessment of PK similarity

A framework for prediction of progression free survival based on modelling of sub-endpoints

Model-informed drug development of autologous CAR-T cell therapy: Strategies to optimize CAR-T cell exposure leveraging cell kinetic/dynamic modeling

Population PK analysis of Pegaspargase in Japanese and non-Japanese patients with acute lymphoblastic leukemia

Application of tumor size modelling and simulations to support the dose selection of BI 907828 for a Phase II study

Potential strategies to optimize CAR-T cell exposure in absence of dose-exposure relationships leveraging cell kinetic/dynamic models

Concentration QTc Analysis of Giredestrant: Overcoming QT/heart rate Confounding in the Presence of Drug-Induced Heart Rate Changes

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