Conference – Pharmetheus

A circular PK/PD/PK model explains the exposure of bulevirtide and bile salts in adult patients with Hepatitis D

A workflow for evaluating and optimizing the designs of paediatric studies

Population pharmacokinetic-pharmacodynamic analysis of elafibranor and metabolite GFT1007 to support exposure-response characterization and dose selection in patients with primary biliary cholangitis

Development of a PBPK model to predict monoclonal antibody pharmacokinetics and bioavailability following subcutaneous administration

Physiologically-based pharmacokinetic (PBPK) modeling to predict disease effects on 5-flucytosine pharmacokinetics (PK) in the context of a switch from an immediate release (IR) to a sustained release (SR) formulation.

A Physiologically Based Pharmacokinetic Model of Atorvastatin Acid Predicting CYP3A4 and OATP1B Drug–Drug Interactions

The reference corrected VPC – A more intuitive model diagnostic

Model-informed early clinical development of BI-1808, a novel monoclonal antibody to tumor necrosis factor receptor 2

Generating uncertainty estimates in empirical forest plots

Optimal design of a reduced sampling schedule for the characterization of prolactin dynamics in healthy male volunteers and its evaluation to the describe the pharmacodynamic effect of a prolactin antagonist in a single rising dose study

Population pharmacokinetic analysis of Datopotamab deruxtecan (Dato-DXd), a TROP2-targeting antibody-drug conjugate.

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