Paul Vrenken, Ph.D.

Associate, MIDD Consultant

Portrait-of-Paul-Vrenken-Pharmetheus-1

Bio

  • Joined Pharmetheus in 2025, actively working in client projects
  • Expertise includes physiologically based pharmacokinetic and biopharmaceutics modeling, and simulation of oral formulations for poorly soluble drugs
  • M.Sc. in Drug Discovery and Safety (2018), from VU Amsterdam, the Netherlands, and Ph.D. in Pharmaceutical Sciences at the National & Kapodistrian University of Athens, Greece
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Pharmetheus affiliated publications

Food effect prediction of high permeability/low solubility, formulated as an amorphous solid dispersion (ASD) using an open systems pharmacology (OSP) PBBM approachPopulation pharmacokinetics and exposure-response analyses of navepegritide in children with achondroplasia