Workshop: PBPK/PD-QSP

This workshop offers hands-on training in Physiologically-based pharmacokinetic (PBPK) modeling with PK-Sim® and MoBi®, focusing on integrating PD and QSP for complex DDIs and special populations like pediatrics and the elderly.

Overview

This workshop covers the development of whole-body PBPK models in PK-Sim®, providing real-world case studies in pediatrics, geriatrics, and DDI scenarios. Participants will learn how to integrate PBPK models with PD and QSP models in MoBi®, including the development of custom-built PD/QSP frameworks for enhanced model flexibility and application.

Workshop goals

Provide participants with a strong foundation to apply PK-Sim® and MoBi® in projects integrating physiological and pharmacological knowledge.

Workshop learning objectives

By the end of this workshop, participants will:

  • Develop whole-body PBPK models in PK-Sim®.
  • Apply PBPK models to case studies in pediatric, elderly, and complex DDI scenarios.
  • Understand the basics of pharmacodynamic (PD) and quantitative systems pharmacology (QSP) modeling in MoBi®.
  • Integrate WB-PBPK models with custom-built PD/QSP models in MoBi®.

Key topics covered

  • Whole-body PBPK modeling in PK-Sim®
  • PBPK applications for pediatric and elderly populations
  • Complex drug-drug interaction (DDI) modeling
  • Integration of PBPK with PD and QSP models
  • Custom-built PD/QSP frameworks in MoBi®

Target audience

This workshop is suitable for scientists and pharmacometricians with some experience in PK-Sim®, looking to advance their skills in PBPK modeling. It is designed for both beginners and advanced users interested in integrating PK-Sim® and MoBi® to develop WB-PBPK-PD/QSP models.

Workshop requirements

Participants must bring a laptop with the required software installed. OSPSuite packages should be installed prior to the workshop.

Ready to discuss your workshop needs?

Email us at communication@pharmetheus.com


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