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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

06.11.23

Exploring the relationship between BI 456906 exposure and change in fasting plasma glucose, fasting serum insulin, and glycated hemoglobin (HbA1c) using population PKPD modeling

Endocrinology

Pharmacometrics

Metabolism

Obesity

ACoP14 (Nov 2023), Poster: M-017

Mc Laughlin AM, Retlich S, Wojtyniak JG, Bergstrand M, Ooi QX, Smania G

06.11.23

Checklists and best practices to support the informed use of Forest plots to illustrate the impact of covariates in pharmacometric models

Pharmacometrics

ACoP14 (Nov 2023), Poster: M-122L

Jonsson EN, Nyberg J

06.11.23

Development of a Physiologically-Based Pharmacokinetic Model for Coproporphyrin I (CP-I) Using the Open Systems Pharmacology Software Suite (PK-Sim and MoBi) for assessment of OATP1B-based DDIs

PBPK & PBBM

Methodology

ACoP14 (Nov 2023), Poster: W-071

Kanacher T, Pellowe M, Kovar C, Eriksson J, Huang F, Wu F, Sailer R, Busse D, Gómez-Mantilla JD

30.10.23

Concentration-QTcF Analysis of Quizartinib in Patients With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

Oncology

MIDD

Regulatory interactions

Pharmacometrics

ACoP13 (Nov 2022), Poster M-034

Vaddady P, Smania G, Bergstrand M, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Sheng M

22.09.23

Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery

PBPK & PBBM

MIDD

QSP

Front. Syst. Biol., 22 September 2023

Reali F, Csikász-Nagy A, Selvaggio G

17.09.23

A disease model predicting placebo response and remission status of patients with ulcerative colitis using modified Mayo score

MIDD

Pharmacometrics

Gastroenterology

Clin Transl Sci. 2023 Sep 17.

Moein A, Langenhorst J, Plan EL, Jin YJ, Kågedal M, Kassir N

07.09.23

Optimized infusion rates for N,N-dimethyltryptamine to achieve a target psychedelic intensity based on a modeling and simulation framework

Trial design and analysis

CNS

CPT Pharmacometrics Syst Pharmacol. 2023 Sep 7.

Eckernäs E, Koomen J, Timmermann C, Carhart-Harris R, Röshammar D, Ashton M

01.09.23

Writing reports of modelling and simulation analysis: Our experience in the field of pharmacometrics

MIDD

Regulatory interactions

Pharmacometrics

Medical Writing. 2023;32(3):56–63

Moroso V, Magnusson MO, Jonsson EN

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