Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery

The research topic highlights how QSP can help streamline the drug development process by employing quantitative frameworks to navigate potential challenges and limitations of the compound candidates, eventually accelerating the drug development process and improving the success rate, bringing new therapies to market.

QSP has quickly gained recognition and importance across various stages of the drug discovery and development process. It plays a multifaceted role, spanning from its application in exploratory research and the identification of drug targets to simulating clinical trials, investigating patient subpopulations, and providing valuable insights for the selection of biomarkers.