QSP services | Pharmetheus

Way of working

At Pharmetheus, our clients’ needs are at the centre of all our projects. This is why we develop fit-for-purpose QSP models, tailored to the specific drug development decisions that need to be informed. We scope the QSP projects upfront, and during the life of the project we draw on the expertise of Pharmetheus MIDD consultants, as well as biologists and physicians.

In line with Pharmetheus valued reputation for its reproducible simulations and excellent regulatory report quality, QSP projects are conducted according to rigorous ways of working, led by integrity, collaboration and dedication.

Pharmetheus dedication to its clients and proven MIDD experience creates the best milieu for QSP modeling and simulation solutions to thrive

Tools

Benefits

Capitalize on the totality of evidence that supports your therapeutic hypothesis

By virtue of its multiscale and mechanistic nature, QSP analyses can support a wide range of drug development decisions.

There are three main areas where it can really complement other Pharmacometrics methods:

Personalized medicine: QSP can help identify novel patient response biomarkers, design optimal sample collection schedules of existing ones, or integrate a Digital Twin strategy with the overall study design.
Novel drug modalities and unprecedented targets: QSP offers a sandpit to optimize the selection of doses & dosing schedules to include in study designs of e.g. drug combinations, bispecific antibodies, cell therapies or mRNA vaccines.
Translational medicine: QSP can make a difference as part of the regulatory evidence package when existing clinical or in vivo model data is scarce or inconclusive.

Way of working

Tools

Capitalize on the totality of evidence that supports your therapeutic hypothesis

Recommended solutions

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