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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

16.08.23

Population Pharmacokinetic Analysis Supports Initiation Treatment and Bridging from Sublingual Buprenorphine to Subcutaneous Administration of a Buprenorphine Depot (CAM2038) in the Treatment of Opioid Use Disorder

Pharmacometrics

CNS

Clin Pharmacokinet . 2023 Oct;62(10):1427-1443

Björnsson MA, Acharya C, Strandgården K, Tiberg F

13.08.23

Training the next generation of pharmacometric modelers: a multisector perspective

PBPK & PBBM

Pharmacometrics

J Pharmacokinet Pharmacodyn. 2024 Feb;51(1):5-31

Bonate P, Barrett J, Ait-Oudhia S, Brundage R, Corrigan B, Duffull S, Gastonguay M, Karlsson MO, Kijima S, Krause A, Lovern M, Neely M, Ouellet D, Plan EL, Rao G, Standing J, Wilkins J, Zhu H

14.07.23

Model-informed drug development of autologous CAR-T cell therapy: Strategies to optimize CAR-T cell exposure leveraging cell kinetic/dynamic modeling

Oncology

MIDD

CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1577-1590

Mc Laughlin AM, Milligan PA, Yee C, Bergstrand M

01.07.23

Virtual patients, digital twins and causal disease models: Paving the ground for in silico clinical trials

PBPK & PBBM

MIDD

Drug Discov Today. 2023 Jul;28(7):103605.

Moingeon P, Chenel M, Rousseau C, Voisin E, Guedj M

27.06.23

Physiologically based pharmacokinetic (PBPK) modeling of the oral absorption of 5-flucytosine to support further development of a sustained-release formulation for the treatment of cryptococcal meningoencephalitis

PBPK & PBBM

MIDD

CNS

Infectious Diseases

PAGE 31 (2023) Abstr 10305

Eriksson J, Sjögren E, Gillon J-Y, Goyal V, Robinson S, Caplain H, Ribeiro I, Chenel M

27.06.23

Target engagement analysis of belimumab in patients with systemic lupus erythematosus (SLE) and primary Sjogren’s syndrome (pSS)

Immunology

Pharmacometrics

Rheumatology

PAGE 31 (2023) Abstr 10371

Dimelow R, Yates J, Salgado E, Mezzalana E

27.06.23

Optimizing infusion rates for N,N-dimethyltryptamine based on either a continuous variable model or a bounded integer model

MIDD

Pharmacometrics

CNS

PAGE 31 (2023) Abstr 10444

Eckernäs E, Koomen J, Timmermann C, Carhart-Harris R, Röshammar D, Ashton M

27.06.23

Use of informative prior distributions from mepolizumab data to support depemokimab PKPD model analysis

Pharmacometrics

Respiratory

PAGE 31 (2023) Abstr 10456

Barceló C, Tanneau L, Acharya C, Ribbing J, Zecchin C, Schalkwijk S

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