Physiologically based pharmacokinetic (PBPK) modeling of the oral absorption of 5-flucytosine to support further development of a sustained-release formulation for the treatment of cryptococcal meningoencephalitis

PBPK & PBBM

MIDD

CNS

Infectious Diseases

Eriksson J, Sjögren E, Gillon J-Y, Goyal V, Robinson S, Caplain H, Ribeiro I, Chenel M