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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

28.06.22

A joint ketamine and esketamine exposure-response model of MADRS score in major depressive disorder to enable informed trial design for candidate drugs with similar mode of action

Trial design and analysis

Pharmacometrics

CNS

PAGE 30 (2022) Abstr 10060

Faraj A, Kristoffersson A, Desch M, Niebecker R

28.06.22

A framework for prediction of progression free survival based on modelling of sub-endpoints

Oncology

Trial design and analysis

Pharmacometrics

PAGE 30 (2022) Abstr 10071

Krishnan SM, Friberg LE, Nyberg J, Sarr C, Niebecker R, Wang S, Perez Pitarch A

28.06.22

Efficient and relevant stepwise covariate model building for pharmacometrics [2]

Pharmacometrics

Automation

PAGE 30 (2022) Abstr 10076

Svensson RJ, Jonsson EN

28.06.22

Physiologically based pharmacokinetic (PBPK) modelling of cabotegravir (CAB) to support design of microarray patches (MAPs) for the treatment of HIV positive children

PBPK & PBBM

Infectious Diseases

PAGE 30 (2022) Abstr 10101

Eriksson J, Sjögren E, Pellowe M, Choy RKM, Mistilis J, Jarrahian C, Zehrung D, Vora LK, Volpe-Zanutto F, Tekko IA, Donnelly RF, Chenel M

28.06.22

A platform for mechanistic modelling of subcutaneous administration with the effect of immunogenicity within the Open Systems Pharmacology framework

PBPK & PBBM

QSP

Immunology

PAGE 30 (2022) Abstr 10129

Pellowe M, Eriksson J, Chenel M, Sjögren E

28.06.22

Rituximab PK and PD evaluation based on a study in diffuse large B-cell lymphoma: influence of tumor size on PK and assessment of PK similarity

Oncology

Pharmacometrics

PAGE 30 (2022) Abstr 10136

Svensson RJ, Ooi QX, Friberg LE, Lopez Lazaro L, Hansson E

28.06.22

Bounded integer model-based analysis of psoriasis area and severity index in patients with moderate-to-severe plaque psoriasis receiving BI 730357 treatment

Immunology

Pharmacometrics

PAGE 30 (2022) Abstr 10209

Ooi QX, Kristoffersson A, Korell J, Flack M, Plan EL, Weber B

10.06.22

Population pharmacokinetic analysis of etrolizumab in patients with moderately-to-severely active ulcerative colitis [2]

Pharmacometrics

Gastroenterology

CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1244-1255

Moein A, Lu T, Jönsson S, Ribbing J, Kassir N, Zhang W, Sperinde G, Zhang R, Tang M, Oh YS, Bruno R

1 …202122… 34

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