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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

30.10.22

Population Pharmacokinetics (PopPK) of Quizartinib and Its Active Metabolite AC886 in Patients (Pts) With Newly Diagnosed (ND) Acute Myeloid Leukemia (AML)

Oncology

MIDD

Regulatory interactions

Pharmacometrics

ACoP13 (Nov 2022), Poster M-027

Vaddady P, Smania G, Glatard A, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Sheng M

30.10.22

An Item Response Theory Model with Bounded Integer Subcomponents to Describe the Mayo Clinic Subscores in Patients with Ulcerative Colitis [2]

Trial design and analysis

Pharmacometrics

Gastroenterology

ACoP13 (Nov 2022), Poster M-048

Moein A, Langenhorst J, Ullah S, Magnusson MO, Jin J, Kassir N

11.09.22

Population Pharmacokinetic/Pharmacodynamic Modeling of the Psychedelic Experience Induced by N,N-dimethyltryptamine - Implications for Dose Considerations

MIDD

Pharmacometrics

CNS

Clin Transl Sci. 2022 Dec;15(12):2928-2937.

Eckernäs E, Timmermann C, Carhart-Harris R, Röshammar D, Ashton M

31.07.22

Imeglimin Population Pharmacokinetics and Dose Adjustment Predictions for Renal Impairment in Japanese and Western Patients with Type 2 Diabetes

MIDD

Endocrinology

Specific populations

Pharmacometrics

Metabolism

Renal diseases

Clin Transl Sci. 2022 Apr;15(4):1014-1026.

Tomita Y, Hansson E, Mazuir F, Wellhagen G, Ooi QX, Mezzalana E, Kitamura A, Nemoto D, Bolze S

19.07.22

Population Pharmacokinetics of Tenecteplase in Patients With Acute Myocardial Infarction and Application to Patients With Acute Ischemic Stroke

MIDD

Cardiovascular

Specific populations

Pharmacometrics

J Clin Pharmacol. 2023 Feb;63(2):197-209. Epub 2022 Nov 23.

Tang F, Langenhorst J, Dang S, Kassir N, Owen R, Purdon B, Magnusson MO, Deng R

19.07.22

Rituximab pharmacokinetic and pharmacokinetic–pharmacodynamic evaluation based on a study in diffuse large B-cell lymphoma: Influence of tumor size on pharmacokinetic and assessment of pharmacokinetic similarity

Oncology

MIDD

Pharmacometrics

Hematology

CPT Pharmacometrics Syst Pharmacol. 2022 Nov 4.

Svensson RJ, Ooi QX, Friberg LE, Maharaj N, Reddy PK, López‐Lázaro L, Hansson E

07.07.22

Efficient and relevant stepwise covariate model building for pharmacometrics [1]

Pharmacometrics

CPT Pharmacometrics Syst Pharmacol. 2022 Jul 19.

Svensson RJ, Jonsson EN

28.06.22

An item response theory model with bounded integer subcomponents to describe the Mayo Clinic subscores in patients with ulcerative colitis

MIDD

Pharmacometrics

Gastroenterology

PAGE 30 (2022) Abstr 10145

Langenhorst J, Moein A, Ullah S, Kågedal M, Magnusson MO, Kassir N

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