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Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

25.06.24

Model-informed early clinical development of BI-1808, a novel monoclonal antibody to tumor necrosis factor receptor 2

Oncology

MIDD

Trial design and analysis

PAGE 32 (2024) Abstr 10786

Mc Laughlin AM, Janssen JM, Borggren M, Teige I, Wallin J

25.06.24

Generating uncertainty estimates in empirical forest plots

Pharmacometrics

Methodology

PAGE 32 (2024) Abstr 11230

Hooker AC, Nyberg J, Jonsson EN

25.06.24

Optimal design of a reduced sampling schedule for the characterization of prolactin dynamics in healthy male volunteers and its evaluation to the describe the pharmacodynamic effect of a prolactin antagonist in a single rising dose study

MIDD

Trial design and analysis

CNS

PAGE 32 (2024) Abstr 10991

Kristoffersson A, Allebrandt K

25.06.24

Population pharmacokinetic analysis of Datopotamab deruxtecan (Dato-DXd), a TROP2-targeting antibody-drug conjugate

Oncology

Trial design and analysis

Pharmacometrics

PAGE 32 (2024) Abstr 10859

Peigné S, Pan Y, Friberg Hietala S, Mc Laughlin AM, Tajima N, Uema D, Zebger-Gong H, Tang Z, Zhou D, Garimella T, Abutarif M, Hong Y

25.06.24

TransCon CNP (Navepegritide): A semi-mechanistic model to describe the prolonged half-life of C-type natriuretic peptide through TransConTM technology

Phase II

Trial design and analysis

Pharmacometrics

Genetic

PAGE 32 (2024) Abstr 11219

Carlsson Petri KC, Antonescu IE, Gallais F, Brekkan A

25.06.24

Absorption, Bioavailability, and Immunogenicity after Subcutaneous Administration: Evaluation of a Subcutaneous Platform within the Open Systems Pharmacology framework

PBPK & PBBM

QSP

Program strategies and efficiencies

PAGE 32 (2024) Abstr 11022

Pellowe M, Selvaggio G, Benamara S, Dubbelboer I, Teutonico D, Chenel M, Sjögren E

25.06.24

Physiologically based pharmacokinetic modelling to support design of microarray patches delivering antiretroviral drugs to HIV positive children.

PBPK & PBBM

Trial design and analysis

Infectious Diseases

PAGE 32 (2024) Abstr 10890

Selvaggio G, Eriksson J, Choy RK, Mistilis J, Kwarteng P, Jarrahian C, Sjögren E, Chenel M

25.06.24

Population pharmacokinetics of survodutide in subjects with overweight or obesity with and without Type 2 Diabetes Mellitus based on Phase I and Phase II data

Endocrinology

Pharmacometrics

Metabolism

Obesity

PAGE 32 (2024) Abstr 11127

Smania G, Glatard A, Bergstrand M, Schmid B, Retlich S, Wojtyniak JG

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