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    Qing Xi Ooi supports clients with hands-on analysis and strategic advice

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  2. Publications

Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

06.01.25

Current State and New Horizons in Applications of Physiologically Based Biopharmaceutics Modeling (PBBM): A Workshop Report

PBPK & PBBM

Mol. Pharmaceutics 2025, 22, 1, 5–27

Tannergren C, Arora S, Babiskin A, Borges L, Chatterjee P, Cheng YH, Dallmann A, Govada A, Heimbach T, Hingle M, Kollipara S, Kotzagiorgis E, Lindahl A, Mackie C, Malamatari M, Mitra A, Moody R, Pepin X, Polli J, Raines K, Rullo G, Sanghavi M, Savkur R, Singh R, Sjögren E, Suarez-Sharp S, Thomas S, Veerasingham S, Wei K, Wu F, Xu Y, Yoon M, Rege B

13.12.24

A tutorial on pharmacometric Markov models

Pharmacometrics

Methodology

CPT Pharmacometrics Syst Pharmacol. 2024;00:1–20.

Ooi QX, Plan EL, Bergstrand M

20.11.24

Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

Oncology

MIDD

Pharmacometrics

Program strategies and efficiencies

Adv Drug Deliv Rev. 2024 Nov 20:115476. Online ahead of print.

Liu H, Ibrahim EIK, Centanni M, Sarr C, Venkatakrishnan K, Friberg LE.

12.11.24

Concentration-QTcF analysis of quizartinib in patients with newly diagnosed FLT3-internal-tandem-duplication-positive acute myeloid leukemia

Oncology

Regulatory interactions

Pharmacometrics

Clin Transl Sci. 2024;17:e70065.

Vaddady P, Smania G, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Zheng M

12.11.24

Population pharmacokinetic analysis of quizartinib in patients with newly diagnosed FLT3-internal-tandem-duplication-positive acute myeloid leukemia

Oncology

Regulatory interactions

Pharmacometrics

Clin Transl Sci. 2024;17:e70074.

Vaddady P, Glatard A, Smania G, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Zheng M

11.11.24

Bimekizumab population pharmacokinetic and exposure-response analyses in adults with moderate to severe hidradenitis suppurativa

Immunology

Pharmacometrics

Program strategies and efficiencies

ACoP15 (Nov 2024), Poster: T-041

Jönsson S, Gallais F, Janssen JM, Rolleri R, Khandelwal A, Dua P, Sidhu J

11.11.24

The impact of misspecified covariate models on inclusion and omission bias when using FREM and FFEM

Pharmacometrics

Methodology

ACoP15 (Nov 2024), Poster: M-051

Jonsson EN, Nyberg J

11.11.24

A novel model for Platelets Dynamics: a pragmatic systems approach to characterize thrombocytopenia across multiple compounds and drug classes

Oncology

MIDD

Hematology

Program strategies and efficiencies

Methodology

ACoP15 (Nov 2024), Poster: T-070

Selvaggio G, Shah Z, Langenhorst J, Yu Z, Friberg LE, Kondic AG

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About Pharmetheus

Pharmetheus is a consultancy firm helping clients reduce uncertainty in technical and regulatory processes, increasing confidence in the development of new medicines that can improve patients’ lives.

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