Skip to content

Main Navigation

  • About us
    • History
    • Mission, vision & values
    • Leadership
    • Scientific advisors
    • Our team
    • Social impact (CSR)
  • Science & Services
    • Contexts of use
      • Trial design and analyses
      • Program strategies and efficiencies
      • Special/specific populations
      • Special considerations
      • Regulatory interactions
    • Pharmetheus Platforms
      • Model-Informed Drug Development
      • PBPK & PBBM
      • Pharmacometrics
      • QSP
    • Solutions
      • Milestone Analysis
      • Embedded Scientist
      • Expert Advice
      • Training workshop
      • Scientific Publication
    • Specific services
      • Model-Informed Bioequivalence & Biosimilarity
    • Publications
    • Case studies
  • Careers
    • Working with us
    • Open positions
    • Employee stories
  • Events
  • News
  • Contact us
  • LinkedIn

A Semi-Mechanistic Model Based on Glutathione Depletion to Describe Intra-Individual Reduction in Busulfan Clearance

Br J Clin Pharmacol. 2020 Aug;86(8):1499-1509.
Langenhorst J, Boss J, van Kesteren C, Lalmohamed A, Kuball J, Egberts ACG, Boelens JJ, Huitema ADR, van Maarseveen EM.
HematologyJournalOncologyPharmacometrics

Pharmetheus Affiliates

Portrait-of-Jurgen-Langenhorst_Pharmetheus
Senior Director, MIDD Consultant

Jurgen Langenhorst

See bio

Contact

Pharmetheus AB
Kungsängstull 4
753 19 Uppsala, Sweden

Visiting address: Dragarbrunnsgatan 77, 5th floor

Contact us

Links

  • Home
  • Newsletter
  • LinkedIn
  • Whistleblower
  • Privacy Policy
  • Cookie Policy
  • Consent Preferences

Services

  • Contexts of use
  • Pharmetheus platforms
  • Solutions
  • Case studies
  • Publications

About

Pharmetheus is a consultancy firm helping clients reduce uncertainty in technical and regulatory processes, increasing confidence in the development of new medicines that can improve patients’ lives.