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    Qing Xi Ooi supports clients with hands-on analysis and strategic advice

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  2. Publications

Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

02.06.26

A structured approach to pharmacometric covariate modelling: why the estimand is the first decision and the method the second

Trial design and analysis

Pharmacometrics

Methodology

PAGE 34 (2026) Abstr 11875

Jonsson EN, Jönsson S, Hansson E, Nyberg J

02.06.26

Model-informed pediatric drug development for clevidipine

MIDD

Specific populations

Pharmacometrics

PAGE 34 (2026) Abstr 12161

Carrara L, Ayoun Alsoud R, Wijk M, Neldemo I, Smania G, Ginocchio V, Bergstrand M, Germani M

02.06.26

The decision-equivalence metric (DEM) method based evaluation of biomarker surrogacy in MASH

Trial design and analysis

Metabolism

Methodology

PAGE 34 (2026) Abstr 12058

Vasyutin I, Glatard A, Stübler S, Fleury A, Schoelch C, Wojtyniak JG

02.06.26

Reference-corrected VPCs: addressing model evaluation challenges with real-world data and adaptive designs

Trial design and analysis

Pharmacometrics

Methodology

PAGE 34 (2026) Abstr 11858

Bergstrand M, Ibrahim MMA, Hughes JH, Keizer RJ

02.06.26

Benchmarking a mechanistic immunogenicity framework: aligning sequence-based epitope predictions with clinical observations

QSP

Immunology

Methodology

PAGE 34 (2026) Abstr 12256

Selvaggio G, Pellowe M, Sjögren E

02.06.26

Implementing a full random effects model (FREM) workflow in R using the saemix package

Pharmacometrics

Automation

Methodology

PAGE 34 (2026) Abstr 12205

Lavalley-Morelle A, Jonsson EN

02.06.26

Usage and regulatory acceptance of PBPK models in paediatric drug applications: a review of EMA and FDA public assessment reports

PBPK & PBBM

MIDD

Regulatory interactions

Specific populations

PAGE 34 (2026) Abstr 12136

Yu C, Ursino M, Retout S, Chenel M, Comets E, Cleary Y.

02.06.26

Population pharmacokinetics and exposure-response analyses of navepegritide in children with achondroplasia

Specific populations

Pharmacometrics

Genetic

PAGE 34 (2026) Abstr 12255

Timmermann S, Zdovc JA, van Eijk M, Clement Freiberg L, Carlsson Petri KC

1234… 34

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About Pharmetheus

Pharmetheus is a consultancy firm helping clients reduce uncertainty in technical and regulatory processes, increasing confidence in the development of new medicines that can improve patients’ lives.

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