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  2. Publications

Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

01.09.18

Applications of Clinically Relevant Dissolution Testing: Workshop Summary Report

PBPK & PBBM

Regulatory interactions

Program strategies and efficiencies

AAPS J. 2018 Aug 27;20(6):93.

Suarez-Sharp S, Cohen M, Kesisoglou F, Abend A, Marroum P, Delvadia P, Kotzagiorgis E, Li M, Nordmark A, Bandi N, Sjögren E, Babiskin A, Heimbach T, Kijima S, Mandula H, Raines K, Seo P, Zhang X

27.08.18

PharmTeX: a LaTeX-Based Open-Source Platform for Automated Reporting Workflow

AAPS J. 2018 Mar 16;20(3):52.

Rasmussen CH, Smith MK, Ito K, Sundararajan V, Magnusson MO, Jonsson EN, Fostvedt L, Burger P, McFadyen L, Tensfeldt TG, Nicholas T

15.08.18

Artemether-Lumefantrine Dosing for Malaria Treatment in Young Children and Pregnant Women: A Pharmacokinetic-Pharmacodynamic Meta-Analysis

Specific populations

Pharmacometrics

Infectious Diseases

PLoS Med. 2018 Jun 12;15(6):e1002579.

Kloprogge F, Workman L, Borrman S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Francesca A, Parikh S, Mwai L, Davis TME, Karunajeewa HA, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux P, Price RN, Karbwang J

01.07.18

Bridging Physiologically Based Pharmacokinetic (PBPK) and Population Pharmacokinetic (PopPK) Analyses in Paediatric Drug Development: A Case Study Based on Intravenous Esomeprazole

PBPK & PBBM

Trial design and analysis

Specific populations

Pharmacometrics

Gastroenterology

PAGE 27 (2018) Abstr 8635.

Kantasiripitak W, Sjögren E, Magnusson MO

01.07.18

Increasing the Efficiency of the Covariate Search Algorithm in the SCM

Pharmacometrics

PAGE 27 (2018) Abstr 8429.

Jonsson EN, Harling K

01.06.18

Model-Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans

Pharmacometrics

Gastroenterology

CPT Pharmacometrics Syst Pharmacol. 2018 Sep;7(9):603-612.

Guiastrennec B, Sonne DP, Bergstrand M, Vilsbøll T, Knop FK, Karlsson MO

01.03.18

A Population Pharmacokinetic-Pharmacodynamic Model of Pegfilgrastim

Oncology

Pharmacometrics

Hematology

AAPS J. 2018 Aug 15;20(5):91.

Brekkan A, Lopez-Lazaro L, Yngman G, Plan EL, Acharya C, Hooker AC, Kankanwadi S, Karlsson MO

01.12.17

Practical Considerations for Using the Full Random Effects Modeling (FREM) Approach to Covariate Modeling

Pharmacometrics

PAGE 26 (2017) Abstr 7365.

Yngman G, Nyberg J, Jonsson EN, Karlsson MO

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About Pharmetheus

Pharmetheus is a consultancy firm helping clients reduce uncertainty in technical and regulatory processes, increasing confidence in the development of new medicines that can improve patients’ lives.

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