Physiologically-based pharmacokinetic (PBPK) modeling to predict disease effects on 5-flucytosine pharmacokinetics (PK) in the context of a switch from an immediate release (IR) to a sustained release (SR) formulation.

PBPK & PBBM

Specific populations

Infectious Diseases

Eriksson J, Sjögren E, Gillon JY, Goyal V, Satam V, Robinson S, Caplain H, Ribeiro I, Chenel M