PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space

PBPK & PBBM

Hematology

Cloesmeijer ME, Sjögren E, Koopman SF, Lenting PJ, Cnossen MH, Mathôt RAA; OPTI‐CLOT study group and SYMPHONY consortium.