Direct and hybrid machine learning approaches do not outperform NLME-based full Bayesian forecasting for early identification of delayed methotrexate elimination

Oncology

Pharmacometrics

Methodology

PAGE 34 (2026) Abstr 11877

Klose M, Marschner D, Knott M, Wendler J, Müller-Kühnle J, Kovar L, Nyhoegen C, Hartung N, Huisinga W, Michelet R, Mc Laughlin AM, Illerhaus G, Kloft C

External authors

Hartung N,

Michelet R,

Huisinga W,

Kloft C,

Klose M,

Marschner D,

Knott M,

Wendler J,

Müller-Kühnle J,

Kovar L,

Nyhoegen C,

Illerhaus G

Pharmetheus collaborators