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    Qing Xi Ooi supports clients with hands-on analysis and strategic advice

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  2. Publications

Publications

Below we provide links to posters, white papers and scientific publications by Pharmetheus affiliates in chronological order. Please note that access to some publications may require a subscription.

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Publications

01.12.19

A PBPK Framework to Predict Drug Exposure in Malnourished Children

PBPK & PBBM

Specific populations

PAGE 28 (2019) Abstr 8968.

Sjögren E, Jonsson EN

08.10.19

Modeling and Simulation of the Modified Rankin Scale and National Institutes of Health Stroke Scale Neurological Endpoints in Intracerebral Hemorrhage

Cardiovascular

Pharmacometrics

CNS

J Pharmacokinet Pharmacodyn. 2019 Oct;46(5):473-484.

Schoemaker R, Nayak S, Harnisch LO, Karlsson MO, on behalf of VISTA-ICH Collaboration

11.07.19

Population PK and PASI Exposure-Response Modelling for Certolizumab Pegol in Patients with Chronic Plaque Psoriasis

Immunology

Pharmacometrics

PAGE 28 (2019) Abstr 9118.

Sarr C, Magnusson MO, Vajjah P, Zamacona M

08.07.19

Effect of Plasma Exchange on the Pharmacokinetics and Pharmacodynamics of Caplacizumab, PS1487

MIDD

Pharmacometrics

Hematology

HemaSphere. 2019 Jun;3(S1):685.

Sargentini L, Hansson E, Bergstrand M, Callewaert F, Sousa RP

08.07.19

Caplacizumab Model-Based Dosing Recommendations in Pediatric Patients with Acquired Thrombotic Thrombocytopenic Purpura, PB2249

MIDD

Specific populations

Pharmacometrics

Hematology

HemaSphere. 2019 Jun;3(S1):1007.

Sargentini L, Hansson E, Bergstrand M, Callewaert F, Sousa RP

13.06.19

Implicit and Efficient Handling of Missing Covariate Information Using Full Random Effects Modelling

Pharmacometrics

PAGE 28 (2019) Abstr 9181.

Nyberg J, Karlsson MO, Jonsson EN

13.06.19

Properties of the Full Random Effect Modelling Approach With Missing Covariates

Pharmacometrics

Preprint. bioRxiv 656470.

Nyberg J, Jonsson EN, Karlsson MO, Häggström J, members of the HBGDki Community

11.06.19

A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab-Treated non-small Cell Lung Cancer Patients

Oncology

Pharmacometrics

Clin Pharmacol Ther. 2019 Feb;105(2):486-495.

Neldemo I, Li CC, Molinero L, Budha N, Sukumaran S, Stroh M, Jonsson EN, Friberg LE

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About Pharmetheus

Pharmetheus is a consultancy firm helping clients reduce uncertainty in technical and regulatory processes, increasing confidence in the development of new medicines that can improve patients’ lives.

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