Will you attend Page 2022 and would benefit from additional insights on a) leveraging in vitro data or b) interpreting covariate effects in models? We have a few last spots left in the two workshops we will be conducting in connection with the conference – find more details below!
The workshop will feature PBPK modelling with the Open Systems Pharmacology suite (OSPS). The combination of use cases based on published examples and hands-on lectures will enable the participants to build their own PBPK projects and maximise their impact by integrating physiological and mechanistic knowledge with preclinical and clinical information. While the workshop is aimed for intermediate levels with PK-Sim® & MoBi®, many topics will be of interest even for beginners or more advanced users.
Marylore Chenel, Ph.D.
Erik Sjögren, Assoc. Prof, Ph.D.
Tobias Kanacher. Ph.D.
Forest plots can be used to efficiently summarize the impact of covariates and other predictors on the primary and secondary parameters from population pharmacokinetic and pharmacodynamic models. They can also be used to illustrate the outcome in important patient subgroups and relate the outcome to observed or hypothetical reference subjects. Forest plots are recommended by regulatory authorities and are becoming a standard component of submission packages to the FDA and other regulatory agencies.
Niclas Jonsson, Ph.D.
Joakim Nyberg, Ph.D.