Our Team
Pharmetheus consultants and advisors present a unique collection of experiences and combination of skill sets.
Chayan Acharya, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2015, actively working in client projects, with continuous improvements, and training Pharmetheus colleagues in R.
- Expertise includes model informed drug development, non-compartmental analysis, and pharmacometrics in therapeutic areas such as immunology, inflammation and analgesia.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he developed an R-package for population pharmacokinetic model diagnosis using non-compartmental analysis metrics, and as Postdoctoral Fellow at University of California San Diego, USA and University of Bordeaux 1, France, with molecular force field development and structure/ligand-based drug design.
- M.Sc. in Physics (2003) from the Indian Institute of Technology Bombay, India, and Ph.D. in Pharmaceutical Sciences (2009) from University of Maryland Baltimore, USA.
Sven Alfredsson
Service Desk Manager
- Joined Pharmetheus in 2021, managing the Service Desk and the incident and request fulfilment processes.
- Expertise includes IT service management processes and tools and IT infrastructure library processes
- Experience as Global Helpdesk Manager at Sirius International, Sweden, where he managed the global helpdesk team. Previously, he worked as Helpdesk Coordinator, Problem & Incident Coordinator, Systems Technician, and Support Technician at Sirius International, Sweden, Systems Technician and IT Technician at ABB, Sweden, and Administration/IT Support at the Swedish Social Insurance Agency.
- Education in ServiceNow Admin and Add Skills Management, Certification in ITIL Capability Stream AOS and ITIL Foundation V3.
Efosa Alohan, M.Sc.
Analyst System Developer
- Joined Pharmetheus in 2022, actively working with tool development and continuous improvement.
- Expertise includes systems and web development.
- Experience as Tech Lead at Ruty and Edventures where he led the tech team to develop e-commerce and educational entrepreneurship platforms.
- M. Sc. in IT Management (2018) from Umeå University, Sweden. Certified Scrum Master and Cisco Certified Network Associate.
Emma Ångström, B.Sc.
Chief Financial Officer
- Joined Pharmetheus in 2016, leading the Business Operations Group and managing the team of Administrative Assistants, Contract Managers and Human Resource Managers.
- Experience as Finance and Administration Manager at Pharmetheus, where she supported the Chief Executive Officer with financial and administrative work and contributed to the planning, monitoring, and follow-up of the business. Previously, she worked as Controller and Manager within Finance and Controlling at the Medical Products Agency, Sweden, Controller and Production Controller at Fresenius Kabi, Sweden, and Auditor at PwC, Sweden.
- B.Sc. in Business Administration and Economics (1996) from Uppsala University, Sweden.
Richard Anziano, M.Sc.
Principal Consultant & Chief Statistician
- Joined Pharmetheus in 2019, actively working in client projects and leading the Science and Policy Team.
- Expertise includes statistics, model informed drug development, and trial design in therapeutic areas such as neuroscience, pain, and infectious diseases.
- Experience as Global Head of Statistics and Chief Statistician at Pfizer Inc, USA, where he led quantitative assessment of late stage probabilities of technical and regulatory success through modeling and simulation for all late stage assets compared to industry or therapeutic area benchmarks. Prior to this role, he had been a member of the statistics leadership for the prior 12 years, led groups of various sizes accountable for the quality and integrity of analyses for those groups, and served as lead statistician for compounds under development.
- M.Sc. in Statistics (1993) from University of Connecticut, USA.
Catalina Barceló, Ph.D.
Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes clinical pharmacology and pharmacometrics in therapeutic areas such as oncology and infectious diseases.
- Experience as PKPD Scientist at Medicines for Malaria Venture, Switzerland, where she provided modeling and simulation support to preclinical and clinical antimalarial programs. Previously, she worked as Clinical Pharmacology and Pharmacometrics Scientist at Debiopharm International, Switzerland, providing support to preclinical and clinical oncology programs.
- Pharmacist (2008) from University of Barcelona, Spain, and Ph.D. in Life Sciences (2018) from University of Lausanne, Switzerland.
Maddlie Bardol, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes pharmacometrics and pediatrics in therapeutic areas such as pain management and sedation.
- M.Sc. in Pharmacometrics (2017) and Pharm.D. (2019) from Paris Descartes University, France, and Ph.D. in Pharmacometrics (2021) from University College London, UK.
Martin Bergstrand, Ph.D.
Principal Consultant
- Co-founded Pharmetheus in 2012, actively working in client projects and with continuous improvements.
- Expertise includes trial design, pharmacometrics (especially complex pharmacokinetics, mechanism based PKPD and Markov models), and model informed drug development in therapeutic areas such as infectious, metabolic, and cardiovascular diseases.
- Experience as part-time Researcher at Uppsala University, Sweden, where he performed pharmacometric research primarily by supervision of Ph.D. students. Previously, he worked as Visiting Scientist at Mahidol-Oxford Tropical Medicine Research Unit, Thailand, and Clinical Pharmacology Scientist at AstraZeneca R&D Mölndal, Sweden.
- M.Sc. in Biomedicine (2003) from University of Kalmar, Sweden, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Marcus Björnsson, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2014, actively working in client projects and serving as Deputy Project Portfolio Team Leader.
- Expertise includes pediatrics and non-compartmental analysis in therapeutic areas such as neuroscience and orphan indications.
- Experience as Neuroscience Therapy Area Pharmacometrics Expert at AstraZeneca R&D, Sweden, where he had strategic and scientific accountability for pharmacometric activities within the neuroscience therapy area. Previously, he worked as Clinical Pharmacokineticist, Senior Research Scientist, and Senior Pharmacometrician at AstraZeneca R&D, Sweden, and Research Scientist at Astra Pain Control, Sweden.
- M.Sc. in Pharmaceutical Sciences (1999) and Ph.D. in Pharmacokinetics and Drug Therapy (2013) from Uppsala University, Sweden.
Ari Brekkan, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes pharmacometrics, especially models for biological medicinal products, and trial design in therapeutic areas such as immunology and haemophilia.
- Experience as temporary Consultant at Pharmetheus where he worked with hands-on application of pharmacometric approaches to support drug development in various therapeutic areas.
- M.Sc. in Drug Discovery and Development (2012) and Ph.D. in Pharmaceutical Science (2019) from Uppsala University, Sweden.
Marylore Chenel, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2021, actively working in client projects, with continuous improvements, and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes model-informed drug development, clinical pharmacology and regulatory advices in therapeutic areas such as oncology/immuno-oncology, immuno-inflammation, cardiology, and diabetes.
- Experience as Head of Global Pharmacometrics and Clinical Pharmacokinetics at Servier, France, where she led a team supporting the drug development portfolio from research to submission including lifecycle management. Previously, she served as Head and Deputy Head of Clinical Pharmacometrics and Clinical Pharmacokinetics, and as a Pharmacometrician at Servier, France, and as Postdoctoral Fellow at the University of Manchester, UK.
- PharmD (2000) and M.Sc. in Pharmacokinetics (2000) from the University of Paris V, France, and Ph.D in Pharmacokinetics – PKPD modeling from the University of Poitiers, France.
Annika Eklund, Ph.D.
QC and Medical Writer
- Joined Pharmetheus in 2021, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes medical writing and quality control across therapeutic areas.
- Experience as Scientific Manager at 3Shape, Denmark, where she performed clinical evaluation of medical devices to document clinical benefits, safety, and performance. Previously, she worked as Global Product Manager Companion Diagnostics at Agilent Technologies, Denmark, Senior Clinical Affairs Specialist at Dako, Denmark, and as Clinical Project Manager Technical Leader, Study Delivery Leader, and Clinical Research Manager at AstraZeneca R&D Lund, Sweden.
- M.Sc. in Molecular Biology (1995) from Umeå University, Sweden, and Ph.D. in Pharmacology (2001) from Linköping University, Sweden.
Johanna Eriksson, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) of preclinical and clinical data, especially for respiratory delivered medicines.
- M.Sc. (2015) and Ph.D. in Pharmaceutical Sciences (2021) from Uppsala University, Sweden.
Georges Etté, M.Sc.
Data Programmer
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes data programming, statistics, and systems development across therapeutic areas.
- Experience as Senior Principal Programmer in Pharmacometrics at Novartis Pharma, Switzerland, where he performed lead programming and data analytic activities across all disease areas. Previously, he worked as Principal Programmer in Statistical Reporting and Principal Programmer in Modeling and Simulation at Novartis Pharma, Switzerland, and Biostatistician at BioStat AS, Norway.
- M.Sc. in Statistics (1997) from University of Pierre et Marie Curie, France.
Magnus Forsbrand, M.Sc.
Board member
- Since 2022, a Pharmetheus Board Member.
- Currently also Chairman of the Board at D&E Bearings AB, Pro Health Pharma Sweden AB, Almi Företagspartner Blekinge AB and Member of the Boards at Gimmersta Wallpaper AB, Safe at Sea AB (publ), Aqua Robur Technologies AB and Cigol AB.
- Experience from over ten Board assignments and four CEO roles in publicly listed and private companies with focus on Growth, Internationalisation and Digitalisation.
- M.Sc. in Electrical Engineering (1990) from Chalmers University of Technology in Gothenburg, Sweden.
Agneta Franksson, M.Sc.
Board Member
- Since 2019, a Pharmetheus Board Member.
- Currently also a member of the board of Arocell AB (Publ.), Sweden, AI Medical Technology AB, and serves as the Chairman of the Board of Directors of Specialplast AB, Ekebygruppen, and Kiselkarbid i Stockholm AB.
- Experience from a CEO role in the clinical research organisation industry as well as other CEO and business development roles in the life science and healthcare industry. Today an accredited teacher at the Swedish Academy of Board Directors.
- M.Sc. in Electrical Engineering and Biomedical Engineering (1987) from the Royal Institute of Technology, Sweden, and MBA in International Business Management (2007) from Uppsala University, Sweden.
Svetlana Freiberga, B.Sc.
Associate Data Programmer
- Joined Pharmetheus in 2018, actively working in client projects.
- Expertise in data programming.
- Experience as Research Assistant and Junior Programmer at Uppsala University, Sweden, where she wrote R code for PsN development, including T markdown code for automated report generation. Previously, she worked as Teacher of Mathematics at Grammar School of Nordic Languages, Latvia.
- B.Sc. in Mathematics and Pedagogy from University of Latvia, Latvia.
- Experience in software development and automated report generation for PsN
- Experience as a teacher of mathematics
Prof. Lena Friberg, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects and training Pharmetheus colleagues in pharmacometrics.
- Expertise includes development of pharmacokinetic-pharmacodynamic models of desired and adverse effects in therapeutic areas such as oncology, infectious diseases, and neuroscience.
- Experience as Professor of Pharmacometrics (2014-2021) and Pharmacokinetics and Pharmacodynamics (2021- ) at Uppsala University, Sweden, where she performs research and teaches in pharmacokinetics, pharmacodynamics, pharmacometrics, and drug development. Previously, she worked as Research Fellow and Associate Professor at Uppsala University, Sweden, and Postdoctoral Research Fellow at University of Queensland, Australia.
- M.Sc. in Pharmaceutical Sciences (1997) and Ph.D. in Pharmacokinetics and Drug Therapy (2003) from Uppsala University, Sweden.
Sofia Friberg Hietala, Ph.D.
Principal Consultant, Team Leader & Board Member
- Joined Pharmetheus in 2015, actively working in client projects and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes clinical pharmacology, trial design, and regulatory advice in therapeutic areas such as metabolic diseases, rheumatology, and infectious diseases.
- Experience as Pharmacokinetics and Pharmacometrics Assessor at the Medical Products Agency, Sweden, where she made scientific assessment of marketing authorization applications, specifically ADME properties, drug-drug interactions, and special populations. Previously, she worked as Senior Clinical Pharmacometrician at AstraZeneca R&D, Sweden, and as Pharmacist at the hospital pharmacy Apoteket SU/Sahlgrenska, Sweden.
- M.Sc. in Pharmacy (1999) from Uppsala University, Sweden, and Ph.D. in Pharmacology from Gothenburg University, Sweden.
Arnaud Gaby, B.Sc.
Senior Data Programmer & Team Leader
- Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and managing the team of Data Programmers.
- Expertise includes systems development and data programming in therapeutic areas such as neuroscience, ophtalmology, immunology, respiratory and oncology.
- Experience as Principal Statistical Programmer in Pharmacometrics at Novartis Pharma, Switzerland, where he prepared modeling datasets for pharmacokinetic-pharmacodynamic analyses and integrated study data from phase I to IV across indications and using different data standards. Previously, he worked as SAS Programmer at the Institut de Recherche Pierre-Fabre, France, and Biostatistician at Aventis Pasteur, France and bioMérieux, France.
- B.Sc. in Statistics and Computing (1997) from the University of the West of England, UK.
Fanny Gallais, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes pharmacometrics within oncology.
- M.Sc. in Bioengineering and Bioinformatics (2017) from National Institute of Applied Sciences of Lyon, France, M.Sc. in Pharmacology and Modeling (2017) from University of Lyon 1, France, and Ph.D. in Pharmacometrics (2020) from the University of Toulouse III Paul Sabatier, France.
Anaïs Glatard, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes clinical pharmacology and pharmacometrics in therapeutic areas such as neuroscience.
- M.Sc. in Pharmacology and modeling, Pharm.D. (2014) from University of Lyon 1, France, and Ph.D. in Life Sciences (2019) from University of Lausanne, Switzerland.
Anna-Lena Granath
Administrative Assistant
- Joined Pharmetheus in 2022, providing administrative support, supporting Client Operations as well as the Communication Team.
- Experience as Executive Assistant at Oasmia Pharmaceutical, Sweden, Sales Support Nordics & Baltics at Iron Mountain, Sweden, and Sales & Marketing Assistant at Recall, Sweden.
- Upper Secondary Diploma in Social Science Program (1992) from Staffanskolan Gymnasium in Söderhamn, Sweden.
Linda Hafdell, B.A.
Contract Manager
- Joined Pharmetheus in 2021, managing customer contracts.
- Experience as Procurement Officer at Uppsala Municipality, Sweden, where she completed procurement documents, led projects, managed supplier dialogues, and followed up on contracts. Previously, she worked as Procurement Officer at Region Uppsala and Uppsala University, Sweden, Bid Manager at Hermods AB, Sweden, and Accounting Assistant at PWC, Sweden.
- B.A. in Business Law / Commercial Law (2015) from Jönköping International Business School, Sweden.
Mikael Haglund, M.Sc.
Human Resources Manager
- Joined Pharmetheus in 2021, working strategically and operationally, developing human resources processes, and leading the People and Policy Team.
- Experience as Human Resources Manager at UR, Swedish Educational Broadcasting Company, where he managed organizational changes, leadership development, and union relations. Previously, he worked as Nordic HR Manager at Opel, Sweden, Nordic HR Director at Dentsu Aegis Network, Sweden, HR Manager at Brothers, Sweden, HR Business Partner at Forsmarks Kraftgrupp AB, Sweden, and Human Resources Generalist at Uppsalahem, Sweden.
- M.Sc. in Human Resources Management and Development (2007) from Umeå University, Sweden.
Emma Hansson, Ph.D.
Senior Consultant, Quality Assurance Officer & Team Leader
- Joined Pharmetheus in 2016, leading the Compliance Team and managing the team of QC and Medical Writing Consultants.
- Expertise includes pediatrics, clinical pharmacology, and regulatory advice in therapeutic areas such as oncology, endocrinology, and infectious diseases.
- Experience as Consultant and Senior MIDD Consultant at Pharmetheus, where she provides advice and hands-on application of pharmacometric approaches to support drug development in various therapeutic areas. Previously, she worked as Pharmacokinetic and Pharmacometric Assessor at the Medical Products Agency, Sweden.
- M.Sc. in Pharmacy (2006) and Ph.D. in Pharmaceutical Biosciences (2012) from Uppsala University, Sweden.
Henrik Hellerstedt
System Administrator
- Joined Pharmetheus in 2020, administering and maintaining IT systems, and participate in the development and renewal of IT infrastructure.
- Expertise includes system administration.
- Experience as IT Manager at AlphaCE Coaching and Education, Sweden, where he administered and maintained IT systems, and planned, organized, controlled, and evaluated IT and electronic data operations. Previously, he worked as IT Manager, System Administrator, and IT Technician at Uppsala Municipality, Sweden, and Founder and CTO at Ecure Datasäkerhet, Sweden.
- Certified Windows Server Administrator and ITIL Foundation certified in IT Service Management
Joakim Hellner, M.Sc.
Associate Data Programmer
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes data programming and systems development.
- Experience as Senior Scientist at Pelago Bioscience AB, Sweden, where he performed data processing, data visualization and full stack web development.
- M.Sc. in Molecular Biotechnology Engineering with orientation Bioinformatics (2016) from Uppsala University, Sweden.
Andrea Henrich, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes QTc analysis, drug-drug interactions, and trial design in therapeutic areas such as oncology, cardiovascular, and immunology.
- Experience as Modeling and Simulation Scientist at Idorsia Pharmaceuticals, Switzerland, where she performed population pharmacokinetic-pharmacodynamic analyses and concentration-QT modeling in different therapeutic areas.
- Pharmacist (2013) from Johann-Wolfgang-Goethe-University, Germany, and Ph.D. in Clinical Pharmacy (2020) from Freie Universitaet Berlin, Germany.
Prof. Andrew Hooker, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects and training Pharmetheus colleagues in pharmacometrics.
- Expertise includes methodological development associated with building, evaluating and using pharmacometric models, trial design (optimal and adaptive experimental design), and application of pharmacometrics in various therapeutic areas.
- Experience as a Professor of Pharmacometrics at Uppsala University, Sweden, where he performs research in pharmacometrics and teaches in pharmacometrics, statistics, and drug development. Previously, he worked as Associate Professor of Pharmacometrics, Assistant Professor of Pharmacometrics, and Postdoctoral Researcher at Uppsala University, Sweden. Co-developer of the software programs Xpose 4 and PsN and the optimal design program PopED.
- M.Sc. in Bioengineering (2001) and Ph.D. in Bioengineering (2003) from the University of Washington, USA.
Moustafa Ibrahim, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes trial design, clinical pharmacology, model informed drug development, and pharmacometrics in therapeutic areas such as hematology, immunology, diabetes, pediatrics, and neurosciences.
- M.Sc. in Clinical Pharmacy (2012) from Helwan University, Egypt, and Ph.D. in Pharmaceutical Biosciences (2019) from Uppsala University, Sweden.
Niclas Jonsson, Ph.D.
Principal Consultant
- Joined Pharmetheus in 2013, actively working in client projects, leading the Continuous Improvement Team, and serving as Project Harmonization Manager.
- Expertise includes pharmacometrics and its applications across therapeutic areas.
- Experience as Senior Consultant at Exprimo NV, Sweden, where he interacted with clients and provided pharmacokinetic, pharmacodynamic, and disease modeling and simulation services to drug development programs in various therapeutic areas. Previously, he worked as Global Head of Modeling and Simulation at Hoffman-La Roche, Switzerland, Associate Professor of Applied Pharmacometrics and Senior Lecturer at Uppsala University, and as Postdoctoral Researcher at University of California San Francisco, USA. Co-developer of the software programs Xpose 4 and PsN
- M.Sc. in Pharmacy (1991) and Ph.D. in Biopharmaceutical Sciences (1998) from Uppsala University, Sweden.
Siv Jönsson, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics, regulatory advice, and pediatric drug development, in hemophilia and across therapeutic areas.
- Experience as Researcher at Uppsala University, Sweden, where she has a part-time position to perform pharmacometric research, primarlily by supervision of Ph.D. students. Previously, she worked as Senior Lecturer and Researcher at Uppsala University, Sweden, Pharmacokinetic Assessor at the Medical Products Agency, Sweden, Senior Research Scientist and Pharmacometrician at AstraZeneca, Sweden, Pharmacokineticist at Kabi Pharma and Kabi Pharmacia, Sweden, and Pharmacist at the Swedish Poison Information Centre, Sweden.
- M.Sc. in Pharmacy (1988) and Ph.D. in Pharmacokinetics and Drug Therapy (2004) from Uppsala University, Sweden.
Tobias Kanacher, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK), pediatrics, and MIDD in therapeutic areas such as oncology, women’s health, and cardiovascular diseases.
- Experience as Consultant Modeling and Simulation at SGS Exprimo NV, Belgium, where he provided advice and hands-on application of pharmacometric approaches to support drug development in various therapeutic areas. Previously, he worked as Systems Pharmacology Expert at Bayer / Bayer Technology Services GmbH, Germany, PBPK Expert in Exploratory ADME at Nycomed: a Takeda Company, Germany, Laboratory Team Leader in Exploratory ADME at Altana Pharma AG / Nycomed Gmbh, Germany, and Laboratory Team and Target-Project Leader in Preclinical Research at Altana Pharma AG, Germany.
- Pharmacist Licensure (1999) from the University Marburg, Germany, and Ph.D. in Pharmaceutical Biochemistry (2003) from the University Tübingen, Germany.
Prof. Mats Karlsson, Ph.D.
Advisor & Chair of the Board
- Co-founded Pharmetheus in 2012, Board Chair and advising on drug development and pharmacometrics.
- Expertise includes methodological development and application of pharmacometrics to drug development and drug usage across therapeutic areas.
- Experience as Professor of Pharmacometrics at Uppsala University, Sweden, where he leads one of the world’s largest research groups in pharmacometrics. Previously, he worked as Professor of Biopharmaceutics and Pharmacokinetics at Uppsala University, Visiting Professor at Georgetown University, USA, Associate Professor at Uppsala University, Sweden, and as Postdoctoral Researcher at University of California, San Francisco, USA, Uppsala University, Sweden, and University of Glasgow, UK.
- M.Sc. in Pharmaceutical Sciences (1984) and Ph.D. in Pharmacokinetics (1989) from Uppsala University, Sweden.
Marie Karlsson
Project Coordinator
- Joined Pharmetheus in 2019, supporting Client Operations throughout the project life cycle.
- Experience as Senior Project Manager and Scrum Master at Aditro, where she managed IT system development projects and applications within the human resources and payroll area. Previously, she worked as Legal Watch, Team Manager, Analyst, and Developer within the IT business.
- Education in Administrative Data Processing (ADB 40p), Umeå kommunala högskola, Sweden.
Antonio Klaric, B.Sc.
Analyst System Administrator
- Joined Pharmetheus in 2019, administering and maintaining IT systems, with focus on providing user support.
- Expertise includes system administration and implementation of ITSM systems.
- Experience as Junior Linux system administrator at Styria IT Solutions, Croatia, where he managed databases, Linux servers, and server-based applications, and provided support to developers.
- B.Sc. in Computer Engineering (2015) from Zagreb Polytechnic for Technical Sciences, Croatia.
Birgit Köster Hoffman, M.Sc.
Board member
- Since 2022, a Pharmetheus Board Member.
- Currently also a member of the Board of Mangold Fondkommission AB (Publ.), Sweden; Auriant Mining AB, Sweden; SaveLend Group AB (Publ.), Sweden and Panthera AB, Sweden. Expertise as Non Executive Board Professional in highly regulated environments, acting as Chairman and Member of the Audit Committee, Risk & Compliance Committee and Credit Committee at various stock-listed entities.
- Experience as CFO and CEO within the Automotive and Financial Services Industry including Leadership and Market Experience in Germany, Italy, Norway, Russia and the Latin American Markets.
- M.Sc. in Economics (1997) from University of Cologne, Germany and PiM in International Management from Copenhagen Business School, Denmark.
Anders Kristoffersson, Ph.D.
Consultant
- Joined Pharmetheus in 2018, actively working in client projects.
- Expertise includes model informed drug development, pharmacometrics, and trial design for pharmacokinetic and pharmacokinetic-pharmacodynamic modelling.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he prepared mechanism based pharmacokinetic-pharmacodynamic models for selection of antibiotic dosing regimens supported by a grant from Hoffman-La Roche.
- M.Sc. in Molecular Biotechnology Engineering (2010) and Ph.D. in Pharmaceutical Biosciences (2015) from Uppsala University, Sweden.
Jurgen Langenhorst, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes pediatrics, QTc analysis, and clinical pharmacology in therapeutic areas such as immunology and oncology.
- Experience as Production Pharmacist at the University Medical Center Utrecht, the Netherlands where he supported daily practise in the manufacturing department of the pharmacy.
- M.Sc. in Pharmacy (2015) from Utrecht University, the Netherlands and Ph.D. in Pharmaceutics (2019) from the University Medical Centre Utrecht, the Netherlands.
Quentin Leirens, M.Sc.
Consultant & System Developer
- Joined Pharmetheus in 2020, actively working in client projects, with tool development, and continuous improvement.
- Expertise includes systems development.
- Experience as Scientist at SGS Exprimo N.V., Belgium, where he performed clinical trial simulations and developed software. Previously, he worked as Scientific Collaborator at Exprimo N.V., Belgium.
- B.Sc. in Engineering Sciences (2009) and M.Sc. in Electrical Engineering (2011) from Université Catholique de Louvain, Belgium.
Mats Magnusson, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2013, actively working in client projects, with continuous improvements, and as Project Portfolio Team Leader managing a team of MIDD Consultants.
- Expertise includes reproducible reporting, pediatrics, and trial design across therapeutic areas.
- Experience as Consultant and Senior Consultant at Exprimo NV, Sweden, where he interacted with clients and provided pharmacokinetic, pharmacodynamic, disease modeling and simulation services to drug development programs in various therapeutic areas. Previously, he worked as Pharmacometrician at Pfizer PGRD, UK.
- M.Sc. in Pharmacy (2001) and Ph.D. in Biopharmaceutical Sciences (2007) from Uppsala University, Sweden.
Anna Mc Laughlin, Dr. rer.nat.
Associate Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes pharmacometrics and model-informed precision dosing of cellular therapies, targeted oral drugs, and targeted drug delivery in therapeutic areas such as oncology and immuno-oncology.
- Pharmacist (2017) and Dr. rer. nat. in Pharmacometrics (2021) from Freie Universitaet Berlin, Germany.
Enrica Mezzalana, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics (especially time-to-event models and target-mediated drug disposition models) and physiological based pharmacokinetic modeling (PBPK, mainly for drug-drug interactions) in therapeutic areas such as oncology, pain, and diabetes.
- Experience as Modeling and Simulation Scientist at SGS Exprimo NV, Belgium, where she developed, interpreted, and reported population pharmacokinetic-pharmacodynamic models, optimal design, and physiological based pharmacokinetic modeling for drug-drug interaction predictions. Previously, she worked as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, and as Postdoctoral Research Fellow at University of Pavia, Italy.
- M.Sc. in Bioengineering (2010) from the University of Padova, Italy, and Ph.D. in Bioengineering and Bioinformatics (2014) from University of Pavia, Italy.
Peter Milligan, Ph.D.
Chief Executive Officer
- Joined Pharmetheus in 2019, serving as managing director for the business, responsible to the Board.
- Expertise includes pre-clinical and clinical pharmacology and pharmacometrics in therapeutic areas such as oncology, neuroscience, and infectious, gastrointestinal, and cardiovascular diseases.
- Experience as Head of Global Pharmacokinetics at Pfizer UK, where he led model informed drug development implementation across Pfizer to develop integrated analyses of relevant data informing strategy, design, and decision making in drug discovery and development. Previously, he worked as Staff Researcher at Syntex, UK.
- M.Sc. in Clinical Pharmacy (1987) from Strathclyde University, UK, and Ph.D. in Medicine and Therapeutics (1991) from Glasgow University, UK.
Viviana Moroso, Ph.D.
Associate QC and Medical Writer
- Joined Pharmetheus in 2020, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes medical writing and quality control across therapeutic areas.
- Experience as freelance Medical Writer and Editor where she prepared publications, conference presentations, medical communications, copyediting for publishers, and provided workshops on academic English writing. Previously, she worked as Laboratory Technician at Unilabs Pathology, Sweden.
- M.Sc. in Medical Biotechnology (2008) from the University of Trieste, Italy, and Ph.D. in Clinical and Basic Immunology (2011) from the Erasmus Medical Center, Rotterdam, the Netherlands.
Georgina Navia Nilsson, M.Sc.
Project Coordinator
- Joined Pharmetheus in 2022, supporting Client Operations throughout the project life cycle.
- Experience as Marketing Communication Manager and Project Manager at Volvo Construction Equipment AB, Sweden, where she managed budgets and developed marketing and communication strategies. Previously, she worked as Regional Market Communication Manager, Nordics at Bluebeam AB, Sweden, and with Marketing and Communication at Wavin, Sweden.
- B.Sc. in Organizational Development and M.Sc. in International Business Economics (2001) from Luleå University of Technology, Sweden.
Ida Neldemo, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics, pediatrics, and trial design in therapeutic areas such as oncology.
- Experience as temporary Consultant at Pharmetheus, Sweden, where she worked with hands-on application of pharmacometric approaches to support drug development.
- M.Sc in Pharmacy (2013) and Ph.D in Pharmaceutical Sciences (2019) from Uppsala University, Sweden.
Joakim Nyberg, Ph.D.
Principal Consultant & Team Leader
- Co-founded Pharmetheus in 2012, actively working in client projects, with continuous improvements, and managing the Enabler Team, including the subteams IT, Data Programming, and Technical Solutions.
- Expertise includes pharmacometrics, trial design, and systems development in therapeutic areas such as diabetes, oncology, and rare diseases.
- Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform pharmacometric research, primarily by supervision of Ph.D. students. Previously, he worked as System Developer at B&M Systemutveckling AB, Sweden.
- M.Sc. in Engineering Physics (2006) and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Marie Olsson
Administrative Assistant
- Joined Pharmetheus in 2019, providing administrative support.
- Experience as Administrative and Security Manager at City Gross Uppsala, Sweden, Store Manager at Willy:s Kungsgatan Uppsala, Sweden, and Manager of the perishable foods at Rätt Pris Uppsala, Sweden.
- Upper Secondary Diploma in Economics (1991) from Vilunda Gymnasium, Sweden.
Qing Xi Ooi, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise in pharmacometrics, quantitative systems pharmacology, and model-informed drug development.
- Experience as B.Pharm. course demonstrator and supervisor at the University of Otago, New Zealand, where she provided tutoring on pharmacokinetics and statistics as well as supervision on pharmacometrics projects. Previously, she worked as a clinical research scientist at the National Clinical Research Centre, Malaysia.
- M.Pharm. (2010) from the University of Manchester, UK, Ph.D. in Pharmacometrics (2018) from the University of Otago, New Zealand.
Sophie Peigné, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes clinical pharmacokinetics, pediatric drug development, in-vitro in-vivo correlation, and pharmacometrics in therapeutic areas such as oncology, immuno-oncology, cardiology, and neurology.
- Experience as PK Project Manager and Principal Pharmacometrician at Servier, France.
- Pharm.D. (2010), Master Degree in Pharmacokinetics (2010), and Ph.D. in Pharmacometrics (2015) from the University of Paris V, France.
Moriah Pellowe, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) and mathematical modeling, in particular cellular automata and systems biology, in therapeutic areas such as oncology.
- Experience as Postdoctoral Fellow at the University of Waterloo, Canada, where she developed a mechanistic inhalation model for drug disposition and an R-package for virtual bioequivalence testing to inform clinical trial design supported by a grant from the FDA, and as Sessional Lecturer at the University of Waterloo, Canada, where she taught undergraduate mathematics courses and a graduate PBPK course.
- B.Sc. in Mathematics (2014) from Redeemer University, Canada, and Ph.D. in Applied Mathematics (2019) from the University of Waterloo, Canada.
Arnaud Pharasyn, M.Sc.
Senior System Administrator & IT Manager
- Joined Pharmetheus in 2013, responsible for all IT systems and managing the IT operations team.
- Expertise includes system administration, systems development, and computerized system validation.
- Experience as Data Programmer at Pharmetheus, Research Engineer at the Swedish National Seismic Network, where he developed a software platform in the field of seismology, administrated and maintained the IT infrastructure and provided user support. Previously, he worked as IT Consultant at Eschelon AB, Sweden, Software Engineer at Mentor Graphics, France, Software Engineer at Ortho-Clinical Diagnostics, France, Consultant at Altran Technologies, France.
- M.Sc. in Physics (1996) from the Ecole Normale Supérieure de Lyon, France.
Elodie Plan, Ph.D.
Principal Consultant
- Co-founded Pharmetheus in 2012, actively working in client projects, leading the Communication Team, and providing management support in Pharmetheus activities.
- Expertise includes model informed drug development, pharmacometrics (especially count data models, Markov models, and item response theory models), and trial design in therapeutic areas such as neuroscience, women’s health, and immunology.
- Experience as Researcher at Uppsala University, where she has a part-time position to perform pharmacometric research, primarily by supervision of Postdoctoral Researchers. Previously, she worked as deputy CEO and Project Portfolio Team Leader at Pharmetheus, Sweden, and Visiting Scientist at Metrum Research Group, USA.
- M.Sc. in Biostatistics (2006) from University Paris Diderot, France, Pharm.D. (2007) from University of Poitiers, France, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Anna Pousette, B.Sc.
Contract Manager & Business Continuity Manager
- Joined Pharmetheus in 2020, managing customer contracts.
- Experience as Project Coordinator at BWN bygg AB, Sweden, where she was responsible for legal, financial, and fiscal aspects. Previously, she worked as Public Procurer at Region Uppsala, Sweden, Account Manager at Landauer Nordic AB, Sweden, Product Specialist ICU/Anesthesia and Nuclear Medicine at Covidien AB, Sweden, Customer Service at Tyco Healthcare AB, Sweden, Elementary School Teacher at Rudenschöldskolan, Sweden, Substitute Teacher at Lidköpings Kommun, Sweden, Sales Representative at AB DJ Stork, Sweden, Medical Interviewer at Lentus Research AB, Sweden, and Product Specialist Insulin Pumps/Anesthesia at Dartec AB, Sweden.
- B. Sc. in Management of Medical Technology (1996) from Stockholms Universitet, Sweden.
Peteris Prusis, Ph.D.
Data Programmer
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes data programming, molecular modelling, QSAR and systems development.
- Experience as Senior Research Scientist at Orion, Finland, where he performed computational chemistry and modeling support for drug discovery. Previously, he worked as Postdoctoral Researcher at AstraZeneca, Sweden, and Assistant Professor at Uppsala University, Sweden.
- M.Sc. in Bioorganic Chemistry (1990) from University of Latvia, Riga, and Ph.D. in Pharmaceutical Biosciences from Uppsala University, Sweden.
Miha Purg, Ph.D.
Associate System Administrator
- Joined Pharmetheus in 2021, administrating IT infrastructure, developing and validating tools, providing user support.
- Expertise includes system administration and systems development.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he performed computational modeling of enzyme function, developed scientific software, designed and administered high performance computing environments.
- M.Sc. in Chemistry (2013) from University of Ljubljana, Slovenia, Ph.D. in Biochemistry (2018) from Uppsala University, Sweden.
Jakob Ribbing, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2014, actively working in client projects and serving as Deputy Project Portfolio Team Leader.
- Expertise includes model-informed drug development, model based meta analysis, and pediatrics in therapeutic areas such as allergy, inflammation, respiratory, neuroscience, and diabetes.
- Experience as Associate Director in Pharmacometrics at Pfizer in UK and Sweden, where he was responsible for team interaction and pharmacometrics deliveries for the Pfizer Allergy and Respiratory portfolio, as well as support to Pfizer global pharmacometrics and clinical pharmacology. Previously, he worked as Manager in Pharmacometrics at Pfizer INC, UK.
- M.Sc. in Pharmacy (2001) and Ph.D. in Biopharmaceutical Sciences (2007) from Uppsala University, Sweden.
Mikael Ringh, Ph.D.
Associate QC and Medical Writer
- Joined Pharmetheus in 2020, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes quality control across therapeutic areas.
- Experience as Postdoctoral Researcher at Karolinska Institutet, Sweden and Pharmaceutical Manufacturing Assistant at GE Healthcare, Norway.
- M.Sc. in Medical Bioscience (2014) from Linköping University, Sweden, and Ph.D. in Medical Science (2019) from Karolinska Institutet, Sweden.
Daniel Röshammar, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2018, actively working in client projects and as Project Portfolio Team Leader managing a team of MIDD Consultants.
- Expertise includes trial design, pediatrics, and regulatory advice in therapeutic areas such as cardiovascular diseases, infectious diseases, and oncology.
- Experience as Managing Director and Scientific Director at SGS Exprimo NV, Belgium, Senior Clinical Pharmacometrician and Section Director Clinical Pharmacometrics at AstraZeneca, Sweden, and Pharmacokineticist and Modeling and Simulation Specialist at Ferring Pharmaceuticals, Denmark.
- M.Sc. in Pharmaceutical Sciences (2003) from Uppsala University, Sweden, and Ph.D. in Medical Sciences (2009) from Gothenburg University, Sweden.
Eric Salgado, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) and non-compartmental analysis in therapeutic areas such as oncology.
- Experience as Pharmacokinetics/Pharmacodynamics Postdoctoral Fellow at IQVIA and University of North Carolina, USA, where he supported hands-on pharmacometric projects such as population pharmacokinetics-pharmacodynamics modeling and simulation, non-compartmental analysis, and physiological based pharmacokinetic modeling including target-mediated drug disposition in the immuno-oncology setting.
- B.Sc. in Chemistry (2013) from the University of Georgia, USA and Ph.D. in Molecular & Systems Pharmacology (2018) from Emory University, USA.
Tomas Salmonson, Ph.D.
Board member
- Since 2022, a Pharmetheus Board Member
- Currently also a partner at Consilium Salmonson & Hemmings, Sweden.
- Experience as Senior Scientific Advisor, Director, and Head of Unit at the Medical Products Agency, Sweden. During that time, he also chaired the Committee for Medicinal Products for Human Use, CHMP, at the European Medicines Agency and before that he was a member of CHMP, representing Sweden.
- M.Sc. in Pharmacy (1986) and Ph.D. in Medicine (1990) from Uppsala University, Sweden.
Marie Sandström, Ph.D.
Chief Operations Officer
- Co-founded Pharmetheus in 2012, managing the Client Operations organization and supporting the Chief Executive Officer in leading the day to day operations of Pharmetheus.
- Expertise includes model informed drug development and clinical pharmacology in therapeutic areas such as neuroscience and oncology.
- Experience as Chief Executive Officer and Senior Consultant at Pharmetheus, where she managed the company and worked actively in client projects, providing clinical pharmacology advice and hands-on application of pharmacometric approaches to support drug development. Previously, she worked as Global Head of Clinical Pharmacometrics, Clinical Pharmacology & DMPK Projects Director Neuroscience, Head of Clinical Pharmacology Södertälje, and Clinical Project Pharmacometrician/Pharmacokineticist at AstraZeneca, Sweden, Lecturer and Associate Professor in Pharmacokinetics and Drug Therapy, Uppsala University, Sweden, and Pharmacist at Apoteksbolaget AB, Sweden.
- M.Sc. in Pharmacy (1989) and Ph.D. in Biopharmaceutical Sciences (2002) from Uppsala University, Sweden.
Céline Sarr, Ph.D.
Senior Consultant & Team Leader
- Joined Pharmetheus in 2016, actively working in client projects, leading the Client Operations Forum, and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes pharmacometrics, submission, pediatric investigation plans, and MIDD support in therapeutic areas such as oncology and metabolism disorders.
- Experience as Senior Consultant at SGS-Exprimo, Belgium, where she delivered modeling results to support submissions and internal decisions. Previously, she worked as Senior Expert Modeler at Novartis, Switzerland, Cluster Leader at Novartis, USA, and Modeler at Novartis, Switzerland.
- Pharm.D. (2004) from University Paris XII, France, and Ph.D. in Pharmaceutical Biosciences (2006) from University Lyon Claude Bernard, France.
Markus Seltmann
Associate System Administrator
- Joined Pharmetheus in 2018, administering and maintaining IT systems, providing user support.
- Expertise in system administration.
- Experience as Apprentice IT Specialist and Junior IT Specialist at ITMC, Technische Universität Dortmund, Germany, where he administered, maintained, and monitored databases, Linux servers and server-based applications.
- IT Specialist for System Integration (2017) from Robert-Bosch-Berufskolleg at Technische Universität Dortmund, Germany.
Prof. Ulrika Simonsson, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects.
- Expertise includes pharmacometrics and model informed drug development with extensive experience in regulatory interactions in therapeutic areas such as infectious diseases, cardiovascular diseases, diabetes, obesity, and cancer.
- Experience as Professor of Pharmacokinetics at Uppsala University, Sweden, where she supervises Ph.D. students in pharmacometrics and gives lectures. Previously, she worked as Senior Research Scientist at AstraZeneca R&D Mölndal, Sweden, Appointed Senior Lecturer and Director of Studies in Pharmacokinetics at Uppsala University, Sweden, Postdoctoral Researcher and Consultant at Pharsight Corporation, USA.
- M.Sc. in Pharmaceutical Sciences (1995) and Ph.D. in Pharmaceutical Biosciences (2000) from Uppsala University, Sweden.
Erik Sjögren, Assoc. Prof, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2017, actively working in client projects.
- Expertise includes physiological based pharmacokinetic and biopharmaceutics modeling and simulation, clinical pharmacology, and pediatrics across therapeutic areas.
- Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform research and supervise Ph.D. students. Previously, he worked as Acting Senior Lecturer at Uppsala University, Sweden and Postdoctoral Researcher at AstraZeneca Mölndal, Sweden.
- M.Sc. in Pharmaceutical Sciences (2004), Ph.D. in Pharmaceutical Sciences (2010), Associate Professor in Biopharmaceutics (2016) from Uppsala University, Sweden.
Giovanni Smania, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and serving as Deputy Project Portfolio Team Leader.
- Expertise includes pharmacometrics (especially translational models, model informed precision dosing and covariate analysis), model informed drug development and in-vitro in-vivo correlation in therapeutic areas such as oncology, neuroscience, and hematology.
- Experience as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, where he supported early clinical development of products in oncology. Previously, he worked as Collaborator and Research Fellow at CVBF, Italy.
- M.Sc. in Bioengineering (2013) and Ph.D. in Bioengineering and Bioinformatics (2017) from University of Pavia, Italy.
Lénaïg Tanneau, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes QTc modeling and pharmacometrics in therapeutic areas such as infectious diseases and oncology.
- Experience as pharmacometrician at Ipsen, France, as contract researcher at Uppsala University in collaboration with Merck KGaA, and as temporary MIDD Consultant at Pharmetheus, Sweden.
- M.Sc. in Pharmacokinetics (2014) from Paris Descartes University, France, Pharm.D. (2015) from University of Nantes, France, and Ph.D. in Pharmacometrics (2022) from Uppsala University, Sweden.
Sami Ullah, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes clinical pharmacology and population pharmacokinetic modeling and simulation of antimicrobial agents in tissues and body fluids.
- Experience as Hospital Pharmacist at PAEC General Hospital, Pakistan and as Lecturer at the Abasyn University Peshawar, Pakistan.
- Pharm.D. (2010) from Gomal University, Pakistan, and Ph.D. in Pharmacy (2020) from University of Bonn, Germany.
Monique Wouters, M.Sc.
Senior QC and Medical Writer
- Started working for Pharmetheus as a subcontractor in 2013, actively working in client projects, with continuous improvements, and training Pharmetheus colleagues in quality control.
- Expertise includes medical writing, quality control, and method development for quality control review of pharmacometric projects across therapeutic areas.
- Experience as Independent Consultant at W&D Consulting bvba, Belgium, where she provided services in clinical pharmacokinetics, medical writing, quality control, and process improvement. Previously, she worked as Global Phase I-IIa Biometrics Manager, Data Review Coordinator, Project Manager Biometrics, and Clinical Data Reviewer at SGS LSS, Belgium, Specialist Clinical Pharmacokinetics at Johnson & Johnson PRD, Belgium, Clinical Data Reviewer at Janssen Research Foundation, Belgium, Marketing positions at Ciba-Geigy, Belgium, and as Administrative and Scientific Assistant at Centraal Laboratorium, Antwerp, Belgium.
Chayan Acharya, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2015, actively working in client projects, with continuous improvements, and training Pharmetheus colleagues in R.
- Expertise includes model informed drug development, non-compartmental analysis, and pharmacometrics in therapeutic areas such as immunology, inflammation and analgesia.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he developed an R-package for population pharmacokinetic model diagnosis using non-compartmental analysis metrics, and as Postdoctoral Fellow at University of California San Diego, USA and University of Bordeaux 1, France, with molecular force field development and structure/ligand-based drug design.
- M.Sc. in Physics (2003) from the Indian Institute of Technology Bombay, India, and Ph.D. in Pharmaceutical Sciences (2009) from University of Maryland Baltimore, USA.
Sven Alfredsson
Service Desk Manager
- Joined Pharmetheus in 2021, managing the Service Desk and the incident and request fulfilment processes.
- Expertise includes IT service management processes and tools and IT infrastructure library processes
- Experience as Global Helpdesk Manager at Sirius International, Sweden, where he managed the global helpdesk team. Previously, he worked as Helpdesk Coordinator, Problem & Incident Coordinator, Systems Technician, and Support Technician at Sirius International, Sweden, Systems Technician and IT Technician at ABB, Sweden, and Administration/IT Support at the Swedish Social Insurance Agency.
- Education in ServiceNow Admin and Add Skills Management, Certification in ITIL Capability Stream AOS and ITIL Foundation V3.
Efosa Alohan, M.Sc.
Analyst System Developer
- Joined Pharmetheus in 2022, actively working with tool development and continuous improvement.
- Expertise includes systems and web development.
- Experience as Tech Lead at Ruty and Edventures where he led the tech team to develop e-commerce and educational entrepreneurship platforms.
- M. Sc. in IT Management (2018) from Umeå University, Sweden. Certified Scrum Master and Cisco Certified Network Associate.
Emma Ångström, B.Sc.
Chief Financial Officer
- Joined Pharmetheus in 2016, leading the Business Operations Group and managing the team of Administrative Assistants, Contract Managers and Human Resource Managers.
- Experience as Finance and Administration Manager at Pharmetheus, where she supported the Chief Executive Officer with financial and administrative work and contributed to the planning, monitoring, and follow-up of the business. Previously, she worked as Controller and Manager within Finance and Controlling at the Medical Products Agency, Sweden, Controller and Production Controller at Fresenius Kabi, Sweden, and Auditor at PwC, Sweden.
- B.Sc. in Business Administration and Economics (1996) from Uppsala University, Sweden.
Richard Anziano, M.Sc.
Principal Consultant & Chief Statistician
- Joined Pharmetheus in 2019, actively working in client projects and leading the Science and Policy Team.
- Expertise includes statistics, model informed drug development, and trial design in therapeutic areas such as neuroscience, pain, and infectious diseases.
- Experience as Global Head of Statistics and Chief Statistician at Pfizer Inc, USA, where he led quantitative assessment of late stage probabilities of technical and regulatory success through modeling and simulation for all late stage assets compared to industry or therapeutic area benchmarks. Prior to this role, he had been a member of the statistics leadership for the prior 12 years, led groups of various sizes accountable for the quality and integrity of analyses for those groups, and served as lead statistician for compounds under development.
- M.Sc. in Statistics (1993) from University of Connecticut, USA.
Catalina Barceló, Ph.D.
Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes clinical pharmacology and pharmacometrics in therapeutic areas such as oncology and infectious diseases.
- Experience as PKPD Scientist at Medicines for Malaria Venture, Switzerland, where she provided modeling and simulation support to preclinical and clinical antimalarial programs. Previously, she worked as Clinical Pharmacology and Pharmacometrics Scientist at Debiopharm International, Switzerland, providing support to preclinical and clinical oncology programs.
- Pharmacist (2008) from University of Barcelona, Spain, and Ph.D. in Life Sciences (2018) from University of Lausanne, Switzerland.
Maddlie Bardol, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes pharmacometrics and pediatrics in therapeutic areas such as pain management and sedation.
- M.Sc. in Pharmacometrics (2017) and Pharm.D. (2019) from Paris Descartes University, France, and Ph.D. in Pharmacometrics (2021) from University College London, UK.
Martin Bergstrand, Ph.D.
Principal Consultant
- Co-founded Pharmetheus in 2012, actively working in client projects and with continuous improvements.
- Expertise includes trial design, pharmacometrics (especially complex pharmacokinetics, mechanism based PKPD and Markov models), and model informed drug development in therapeutic areas such as infectious, metabolic, and cardiovascular diseases.
- Experience as part-time Researcher at Uppsala University, Sweden, where he performed pharmacometric research primarily by supervision of Ph.D. students. Previously, he worked as Visiting Scientist at Mahidol-Oxford Tropical Medicine Research Unit, Thailand, and Clinical Pharmacology Scientist at AstraZeneca R&D Mölndal, Sweden.
- M.Sc. in Biomedicine (2003) from University of Kalmar, Sweden, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Marcus Björnsson, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2014, actively working in client projects and serving as Deputy Project Portfolio Team Leader.
- Expertise includes pediatrics and non-compartmental analysis in therapeutic areas such as neuroscience and orphan indications.
- Experience as Neuroscience Therapy Area Pharmacometrics Expert at AstraZeneca R&D, Sweden, where he had strategic and scientific accountability for pharmacometric activities within the neuroscience therapy area. Previously, he worked as Clinical Pharmacokineticist, Senior Research Scientist, and Senior Pharmacometrician at AstraZeneca R&D, Sweden, and Research Scientist at Astra Pain Control, Sweden.
- M.Sc. in Pharmaceutical Sciences (1999) and Ph.D. in Pharmacokinetics and Drug Therapy (2013) from Uppsala University, Sweden.
Ari Brekkan, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes pharmacometrics, especially models for biological medicinal products, and trial design in therapeutic areas such as immunology and haemophilia.
- Experience as temporary Consultant at Pharmetheus where he worked with hands-on application of pharmacometric approaches to support drug development in various therapeutic areas.
- M.Sc. in Drug Discovery and Development (2012) and Ph.D. in Pharmaceutical Science (2019) from Uppsala University, Sweden.
Anna Chan Kwong, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes pharmacometrics and pediatrics in therapeutic areas such as infectious diseases and immunology.
- M.Sc. in Biostatistics (2018), PharmD and Ph.D. in Pharmacometrics (2021) from Aix-Marseille University, France.
Marylore Chenel, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2021, actively working in client projects, with continuous improvements, and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes model-informed drug development, clinical pharmacology and regulatory advices in therapeutic areas such as oncology/immuno-oncology, immuno-inflammation, cardiology, and diabetes.
- Experience as Head of Global Pharmacometrics and Clinical Pharmacokinetics at Servier, France, where she led a team supporting the drug development portfolio from research to submission including lifecycle management. Previously, she served as Head and Deputy Head of Clinical Pharmacometrics and Clinical Pharmacokinetics, and as a Pharmacometrician at Servier, France, and as Postdoctoral Fellow at the University of Manchester, UK.
- PharmD (2000) and M.Sc. in Pharmacokinetics (2000) from the University of Paris V, France, and Ph.D in Pharmacokinetics – PKPD modeling from the University of Poitiers, France.
Ricardo Danza, B.Sc.
Analyst Systems Developer
- Joined Pharmetheus in 2021, actively working with tool development and continuous improvement.
- Expertise includes systems development.
- B.Sc. in Computer Science (2019) from Uppsala University, Sweden.
Patrik Ejerhed, B.Sc.
Financial Controller
- Joined Pharmetheus in 2022, working with the CFO and further bolstering the finance function.
- Experience as Senior Audit Associate at PwC and Audit Associate at KPMG.
- B.Sc. in Business Administration and Economics (2019) from Uppsala University,
Sweden.
Annika Eklund, Ph.D.
QC and Medical Writer
- Joined Pharmetheus in 2021, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes medical writing and quality control across therapeutic areas.
- Experience as Scientific Manager at 3Shape, Denmark, where she performed clinical evaluation of medical devices to document clinical benefits, safety, and performance. Previously, she worked as Global Product Manager Companion Diagnostics at Agilent Technologies, Denmark, Senior Clinical Affairs Specialist at Dako, Denmark, and as Clinical Project Manager Technical Leader, Study Delivery Leader, and Clinical Research Manager at AstraZeneca R&D Lund, Sweden.
- M.Sc. in Molecular Biology (1995) from Umeå University, Sweden, and Ph.D. in Pharmacology (2001) from Linköping University, Sweden.
Johanna Eriksson, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) of preclinical and clinical data, especially for respiratory delivered medicines.
- M.Sc. (2015) and Ph.D. in Pharmaceutical Sciences (2021) from Uppsala University, Sweden.
Georges Etté, M.Sc.
Data Programmer
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes data programming, statistics, and systems development across therapeutic areas.
- Experience as Senior Principal Programmer in Pharmacometrics at Novartis Pharma, Switzerland, where he performed lead programming and data analytic activities across all disease areas. Previously, he worked as Principal Programmer in Statistical Reporting and Principal Programmer in Modeling and Simulation at Novartis Pharma, Switzerland, and Biostatistician at BioStat AS, Norway.
- M.Sc. in Statistics (1997) from University of Pierre et Marie Curie, France.
Magnus Forsbrand, M.Sc.
Board member
- Since 2022, a Pharmetheus Board Member.
- Currently also Chairman of the Board at D&E Bearings AB, Pro Health Pharma Sweden AB, Almi Företagspartner Blekinge AB and Member of the Boards at Gimmersta Wallpaper AB, Safe at Sea AB (publ), Aqua Robur Technologies AB and Cigol AB.
- Experience from over ten Board assignments and four CEO roles in publicly listed and private companies with focus on Growth, Internationalisation and Digitalisation.
- M.Sc. in Electrical Engineering (1990) from Chalmers University of Technology in Gothenburg, Sweden.
Agneta Franksson, M.Sc.
Board Member
- Since 2019, a Pharmetheus Board Member.
- Currently also a member of the board of Arocell AB (Publ.), Sweden, AI Medical Technology AB, and serves as the Chairman of the Board of Directors of Specialplast AB, Ekebygruppen, and Kiselkarbid i Stockholm AB.
- Experience from a CEO role in the clinical research organisation industry as well as other CEO and business development roles in the life science and healthcare industry. Today an accredited teacher at the Swedish Academy of Board Directors.
- M.Sc. in Electrical Engineering and Biomedical Engineering (1987) from the Royal Institute of Technology, Sweden, and MBA in International Business Management (2007) from Uppsala University, Sweden.
Svetlana Freiberga, B.Sc.
Associate Data Programmer
- Joined Pharmetheus in 2018, actively working in client projects.
- Expertise in data programming.
- Experience as Research Assistant and Junior Programmer at Uppsala University, Sweden, where she wrote R code for PsN development, including T markdown code for automated report generation. Previously, she worked as Teacher of Mathematics at Grammar School of Nordic Languages, Latvia.
- B.Sc. in Mathematics and Pedagogy from University of Latvia, Latvia.
- Experience in software development and automated report generation for PsN
- Experience as a teacher of mathematics
Prof. Lena Friberg, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects and training Pharmetheus colleagues in pharmacometrics.
- Expertise includes development of pharmacokinetic-pharmacodynamic models of desired and adverse effects in therapeutic areas such as oncology, infectious diseases, and neuroscience.
- Experience as Professor of Pharmacometrics (2014-2021) and Pharmacokinetics and Pharmacodynamics (2021- ) at Uppsala University, Sweden, where she performs research and teaches in pharmacokinetics, pharmacodynamics, pharmacometrics, and drug development. Previously, she worked as Research Fellow and Associate Professor at Uppsala University, Sweden, and Postdoctoral Research Fellow at University of Queensland, Australia.
- M.Sc. in Pharmaceutical Sciences (1997) and Ph.D. in Pharmacokinetics and Drug Therapy (2003) from Uppsala University, Sweden.
Sofia Friberg Hietala, Ph.D.
Principal Consultant, Team Leader & Board Member
- Joined Pharmetheus in 2015, actively working in client projects and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes clinical pharmacology, trial design, and regulatory advice in therapeutic areas such as metabolic diseases, rheumatology, and infectious diseases.
- Experience as Pharmacokinetics and Pharmacometrics Assessor at the Medical Products Agency, Sweden, where she made scientific assessment of marketing authorization applications, specifically ADME properties, drug-drug interactions, and special populations. Previously, she worked as Senior Clinical Pharmacometrician at AstraZeneca R&D, Sweden, and as Pharmacist at the hospital pharmacy Apoteket SU/Sahlgrenska, Sweden.
- M.Sc. in Pharmacy (1999) from Uppsala University, Sweden, and Ph.D. in Pharmacology from Gothenburg University, Sweden.
Arnaud Gaby, B.Sc.
Senior Data Programmer & Team Leader
- Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and managing the team of Data Programmers.
- Expertise includes systems development and data programming in therapeutic areas such as neuroscience, ophtalmology, immunology, respiratory and oncology.
- Experience as Principal Statistical Programmer in Pharmacometrics at Novartis Pharma, Switzerland, where he prepared modeling datasets for pharmacokinetic-pharmacodynamic analyses and integrated study data from phase I to IV across indications and using different data standards. Previously, he worked as SAS Programmer at the Institut de Recherche Pierre-Fabre, France, and Biostatistician at Aventis Pasteur, France and bioMérieux, France.
- B.Sc. in Statistics and Computing (1997) from the University of the West of England, UK.
Fanny Gallais, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes pharmacometrics within oncology.
- M.Sc. in Bioengineering and Bioinformatics (2017) from National Institute of Applied Sciences of Lyon, France, M.Sc. in Pharmacology and Modeling (2017) from University of Lyon 1, France, and Ph.D. in Pharmacometrics (2020) from the University of Toulouse III Paul Sabatier, France.
Anaïs Glatard, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes clinical pharmacology and pharmacometrics in therapeutic areas such as neuroscience.
- M.Sc. in Pharmacology and modeling, Pharm.D. (2014) from University of Lyon 1, France, and Ph.D. in Life Sciences (2019) from University of Lausanne, Switzerland.
Anna-Lena Granath
Administrative Assistant
- Joined Pharmetheus in 2022, providing administrative support, supporting Client Operations as well as the Communication Team.
- Experience as Executive Assistant at Oasmia Pharmaceutical, Sweden, Sales Support Nordics & Baltics at Iron Mountain, Sweden, and Sales & Marketing Assistant at Recall, Sweden.
- Upper Secondary Diploma in Social Science Program (1992) from Staffanskolan Gymnasium in Söderhamn, Sweden.
Linda Hafdell, B.A.
Contract Manager
- Joined Pharmetheus in 2021, managing customer contracts.
- Experience as Procurement Officer at Uppsala Municipality, Sweden, where she completed procurement documents, led projects, managed supplier dialogues, and followed up on contracts. Previously, she worked as Procurement Officer at Region Uppsala and Uppsala University, Sweden, Bid Manager at Hermods AB, Sweden, and Accounting Assistant at PWC, Sweden.
- B.A. in Business Law / Commercial Law (2015) from Jönköping International Business School, Sweden.
Mikael Haglund, M.Sc.
Human Resources Manager
- Joined Pharmetheus in 2021, working strategically and operationally, developing human resources processes, and leading the People and Policy Team.
- Experience as Human Resources Manager at UR, Swedish Educational Broadcasting Company, where he managed organizational changes, leadership development, and union relations. Previously, he worked as Nordic HR Manager at Opel, Sweden, Nordic HR Director at Dentsu Aegis Network, Sweden, HR Manager at Brothers, Sweden, HR Business Partner at Forsmarks Kraftgrupp AB, Sweden, and Human Resources Generalist at Uppsalahem, Sweden.
- M.Sc. in Human Resources Management and Development (2007) from Umeå University, Sweden.
Emma Hansson, Ph.D.
Senior Consultant, Quality Assurance Officer & Team Leader
- Joined Pharmetheus in 2016, leading the Compliance Team and managing the team of QC and Medical Writing Consultants.
- Expertise includes pediatrics, clinical pharmacology, and regulatory advice in therapeutic areas such as oncology, endocrinology, and infectious diseases.
- Experience as Consultant and Senior MIDD Consultant at Pharmetheus, where she provides advice and hands-on application of pharmacometric approaches to support drug development in various therapeutic areas. Previously, she worked as Pharmacokinetic and Pharmacometric Assessor at the Medical Products Agency, Sweden.
- M.Sc. in Pharmacy (2006) and Ph.D. in Pharmaceutical Biosciences (2012) from Uppsala University, Sweden.
Henrik Hellerstedt
System Administrator
- Joined Pharmetheus in 2020, administering and maintaining IT systems, and participate in the development and renewal of IT infrastructure.
- Expertise includes system administration.
- Experience as IT Manager at AlphaCE Coaching and Education, Sweden, where he administered and maintained IT systems, and planned, organized, controlled, and evaluated IT and electronic data operations. Previously, he worked as IT Manager, System Administrator, and IT Technician at Uppsala Municipality, Sweden, and Founder and CTO at Ecure Datasäkerhet, Sweden.
- Certified Windows Server Administrator and ITIL Foundation certified in IT Service Management
Joakim Hellner, M.Sc.
Associate Data Programmer
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes data programming and systems development.
- Experience as Senior Scientist at Pelago Bioscience AB, Sweden, where he performed data processing, data visualization and full stack web development.
- M.Sc. in Molecular Biotechnology Engineering with orientation Bioinformatics (2016) from Uppsala University, Sweden.
Andrea Henrich, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes QTc analysis, drug-drug interactions, and trial design in therapeutic areas such as oncology, cardiovascular, and immunology.
- Experience as Modeling and Simulation Scientist at Idorsia Pharmaceuticals, Switzerland, where she performed population pharmacokinetic-pharmacodynamic analyses and concentration-QT modeling in different therapeutic areas.
- Pharmacist (2013) from Johann-Wolfgang-Goethe-University, Germany, and Ph.D. in Clinical Pharmacy (2020) from Freie Universitaet Berlin, Germany.
Prof. Andrew Hooker, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects and training Pharmetheus colleagues in pharmacometrics.
- Expertise includes methodological development associated with building, evaluating and using pharmacometric models, trial design (optimal and adaptive experimental design), and application of pharmacometrics in various therapeutic areas.
- Experience as a Professor of Pharmacometrics at Uppsala University, Sweden, where he performs research in pharmacometrics and teaches in pharmacometrics, statistics, and drug development. Previously, he worked as Associate Professor of Pharmacometrics, Assistant Professor of Pharmacometrics, and Postdoctoral Researcher at Uppsala University, Sweden. Co-developer of the software programs Xpose 4 and PsN and the optimal design program PopED.
- M.Sc. in Bioengineering (2001) and Ph.D. in Bioengineering (2003) from the University of Washington, USA.
Moustafa Ibrahim, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes trial design, clinical pharmacology, model informed drug development, and pharmacometrics in therapeutic areas such as hematology, immunology, diabetes, pediatrics, and neurosciences.
- M.Sc. in Clinical Pharmacy (2012) from Helwan University, Egypt, and Ph.D. in Pharmaceutical Biosciences (2019) from Uppsala University, Sweden.
Julie Janssen, Ph.D.
Consultant
- Joined Pharmetheus in 2020, actively working in client projects.
- Expertise includes clinical pharmacology, model informed drug development, and pharmacometrics in therapeutic areas such as oncology.
- M.Sc. in Pharmacy (2016) and Ph.D. in Medicine (2020) from Utrecht University, The Netherlands
Niclas Jonsson, Ph.D.
Principal Consultant
- Joined Pharmetheus in 2013, actively working in client projects, leading the Continuous Improvement Team, and serving as Project Harmonization Manager.
- Expertise includes pharmacometrics and its applications across therapeutic areas.
- Experience as Senior Consultant at Exprimo NV, Sweden, where he interacted with clients and provided pharmacokinetic, pharmacodynamic, and disease modeling and simulation services to drug development programs in various therapeutic areas. Previously, he worked as Global Head of Modeling and Simulation at Hoffman-La Roche, Switzerland, Associate Professor of Applied Pharmacometrics and Senior Lecturer at Uppsala University, and as Postdoctoral Researcher at University of California San Francisco, USA. Co-developer of the software programs Xpose 4 and PsN
- M.Sc. in Pharmacy (1991) and Ph.D. in Biopharmaceutical Sciences (1998) from Uppsala University, Sweden.
Siv Jönsson, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics, regulatory advice, and pediatric drug development, in hemophilia and across therapeutic areas.
- Experience as Researcher at Uppsala University, Sweden, where she has a part-time position to perform pharmacometric research, primarlily by supervision of Ph.D. students. Previously, she worked as Senior Lecturer and Researcher at Uppsala University, Sweden, Pharmacokinetic Assessor at the Medical Products Agency, Sweden, Senior Research Scientist and Pharmacometrician at AstraZeneca, Sweden, Pharmacokineticist at Kabi Pharma and Kabi Pharmacia, Sweden, and Pharmacist at the Swedish Poison Information Centre, Sweden.
- M.Sc. in Pharmacy (1988) and Ph.D. in Pharmacokinetics and Drug Therapy (2004) from Uppsala University, Sweden.
Tobias Kanacher, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK), pediatrics, and MIDD in therapeutic areas such as oncology, women’s health, and cardiovascular diseases.
- Experience as Consultant Modeling and Simulation at SGS Exprimo NV, Belgium, where he provided advice and hands-on application of pharmacometric approaches to support drug development in various therapeutic areas. Previously, he worked as Systems Pharmacology Expert at Bayer / Bayer Technology Services GmbH, Germany, PBPK Expert in Exploratory ADME at Nycomed: a Takeda Company, Germany, Laboratory Team Leader in Exploratory ADME at Altana Pharma AG / Nycomed Gmbh, Germany, and Laboratory Team and Target-Project Leader in Preclinical Research at Altana Pharma AG, Germany.
- Pharmacist Licensure (1999) from the University Marburg, Germany, and Ph.D. in Pharmaceutical Biochemistry (2003) from the University Tübingen, Germany.
Prof. Mats Karlsson, Ph.D.
Advisor & Chair of the Board
- Co-founded Pharmetheus in 2012, Board Chair and advising on drug development and pharmacometrics.
- Expertise includes methodological development and application of pharmacometrics to drug development and drug usage across therapeutic areas.
- Experience as Professor of Pharmacometrics at Uppsala University, Sweden, where he leads one of the world’s largest research groups in pharmacometrics. Previously, he worked as Professor of Biopharmaceutics and Pharmacokinetics at Uppsala University, Visiting Professor at Georgetown University, USA, Associate Professor at Uppsala University, Sweden, and as Postdoctoral Researcher at University of California, San Francisco, USA, Uppsala University, Sweden, and University of Glasgow, UK.
- M.Sc. in Pharmaceutical Sciences (1984) and Ph.D. in Pharmacokinetics (1989) from Uppsala University, Sweden.
Marie Karlsson
Project Coordinator
- Joined Pharmetheus in 2019, supporting Client Operations throughout the project life cycle.
- Experience as Senior Project Manager and Scrum Master at Aditro, where she managed IT system development projects and applications within the human resources and payroll area. Previously, she worked as Legal Watch, Team Manager, Analyst, and Developer within the IT business.
- Education in Administrative Data Processing (ADB 40p), Umeå kommunala högskola, Sweden.
Antonio Klaric, B.Sc.
Analyst System Administrator
- Joined Pharmetheus in 2019, administering and maintaining IT systems, with focus on providing user support.
- Expertise includes system administration and implementation of ITSM systems.
- Experience as Junior Linux system administrator at Styria IT Solutions, Croatia, where he managed databases, Linux servers, and server-based applications, and provided support to developers.
- B.Sc. in Computer Engineering (2015) from Zagreb Polytechnic for Technical Sciences, Croatia.
Birgit Köster Hoffman, M.Sc.
Board member
- Since 2022, a Pharmetheus Board Member.
- Currently also a member of the Board of Mangold Fondkommission AB (Publ.), Sweden; Auriant Mining AB, Sweden; SaveLend Group AB (Publ.), Sweden and Panthera AB, Sweden. Expertise as Non Executive Board Professional in highly regulated environments, acting as Chairman and Member of the Audit Committee, Risk & Compliance Committee and Credit Committee at various stock-listed entities.
- Experience as CFO and CEO within the Automotive and Financial Services Industry including Leadership and Market Experience in Germany, Italy, Norway, Russia and the Latin American Markets.
- M.Sc. in Economics (1997) from University of Cologne, Germany and PiM in International Management from Copenhagen Business School, Denmark.
Anders Kristoffersson, Ph.D.
Consultant
- Joined Pharmetheus in 2018, actively working in client projects.
- Expertise includes model informed drug development, pharmacometrics, and trial design for pharmacokinetic and pharmacokinetic-pharmacodynamic modelling.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he prepared mechanism based pharmacokinetic-pharmacodynamic models for selection of antibiotic dosing regimens supported by a grant from Hoffman-La Roche.
- M.Sc. in Molecular Biotechnology Engineering (2010) and Ph.D. in Pharmaceutical Biosciences (2015) from Uppsala University, Sweden.
Jurgen Langenhorst, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise includes pediatrics, QTc analysis, and clinical pharmacology in therapeutic areas such as immunology and oncology.
- Experience as Production Pharmacist at the University Medical Center Utrecht, the Netherlands where he supported daily practise in the manufacturing department of the pharmacy.
- M.Sc. in Pharmacy (2015) from Utrecht University, the Netherlands and Ph.D. in Pharmaceutics (2019) from the University Medical Centre Utrecht, the Netherlands.
Quentin Leirens, M.Sc.
Consultant & System Developer
- Joined Pharmetheus in 2020, actively working in client projects, with tool development, and continuous improvement.
- Expertise includes systems development.
- Experience as Scientist at SGS Exprimo N.V., Belgium, where he performed clinical trial simulations and developed software. Previously, he worked as Scientific Collaborator at Exprimo N.V., Belgium.
- B.Sc. in Engineering Sciences (2009) and M.Sc. in Electrical Engineering (2011) from Université Catholique de Louvain, Belgium.
Per Lundström, B.Sc.
Administrative Assistant
- Joined Pharmetheus in 2018, providing administrative and communication support, and managing customer contracts.
- Experience in administration, commercial photography, advertising and graphical design.
- B.Sc. in Behavioral Sciences (2018) from Uppsala University, Sweden.
Mats Magnusson, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2013, actively working in client projects, with continuous improvements, and as Project Portfolio Team Leader managing a team of MIDD Consultants.
- Expertise includes reproducible reporting, pediatrics, and trial design across therapeutic areas.
- Experience as Consultant and Senior Consultant at Exprimo NV, Sweden, where he interacted with clients and provided pharmacokinetic, pharmacodynamic, disease modeling and simulation services to drug development programs in various therapeutic areas. Previously, he worked as Pharmacometrician at Pfizer PGRD, UK.
- M.Sc. in Pharmacy (2001) and Ph.D. in Biopharmaceutical Sciences (2007) from Uppsala University, Sweden.
Anna Mc Laughlin, Dr. rer.nat.
Associate Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes pharmacometrics and model-informed precision dosing of cellular therapies, targeted oral drugs, and targeted drug delivery in therapeutic areas such as oncology and immuno-oncology.
- Pharmacist (2017) and Dr. rer. nat. in Pharmacometrics (2021) from Freie Universitaet Berlin, Germany.
Enrica Mezzalana, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics (especially time-to-event models and target-mediated drug disposition models) and physiological based pharmacokinetic modeling (PBPK, mainly for drug-drug interactions) in therapeutic areas such as oncology, pain, and diabetes.
- Experience as Modeling and Simulation Scientist at SGS Exprimo NV, Belgium, where she developed, interpreted, and reported population pharmacokinetic-pharmacodynamic models, optimal design, and physiological based pharmacokinetic modeling for drug-drug interaction predictions. Previously, she worked as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, and as Postdoctoral Research Fellow at University of Pavia, Italy.
- M.Sc. in Bioengineering (2010) from the University of Padova, Italy, and Ph.D. in Bioengineering and Bioinformatics (2014) from University of Pavia, Italy.
Peter Milligan, Ph.D.
Chief Executive Officer
- Joined Pharmetheus in 2019, serving as managing director for the business, responsible to the Board.
- Expertise includes pre-clinical and clinical pharmacology and pharmacometrics in therapeutic areas such as oncology, neuroscience, and infectious, gastrointestinal, and cardiovascular diseases.
- Experience as Head of Global Pharmacokinetics at Pfizer UK, where he led model informed drug development implementation across Pfizer to develop integrated analyses of relevant data informing strategy, design, and decision making in drug discovery and development. Previously, he worked as Staff Researcher at Syntex, UK.
- M.Sc. in Clinical Pharmacy (1987) from Strathclyde University, UK, and Ph.D. in Medicine and Therapeutics (1991) from Glasgow University, UK.
Viviana Moroso, Ph.D.
Associate QC and Medical Writer
- Joined Pharmetheus in 2020, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes medical writing and quality control across therapeutic areas.
- Experience as freelance Medical Writer and Editor where she prepared publications, conference presentations, medical communications, copyediting for publishers, and provided workshops on academic English writing. Previously, she worked as Laboratory Technician at Unilabs Pathology, Sweden.
- M.Sc. in Medical Biotechnology (2008) from the University of Trieste, Italy, and Ph.D. in Clinical and Basic Immunology (2011) from the Erasmus Medical Center, Rotterdam, the Netherlands.
Georgina Navia Nilsson, M.Sc.
Project Coordinator
- Joined Pharmetheus in 2022, supporting Client Operations throughout the project life cycle.
- Experience as Marketing Communication Manager and Project Manager at Volvo Construction Equipment AB, Sweden, where she managed budgets and developed marketing and communication strategies. Previously, she worked as Regional Market Communication Manager, Nordics at Bluebeam AB, Sweden, and with Marketing and Communication at Wavin, Sweden.
- B.Sc. in Organizational Development and M.Sc. in International Business Economics (2001) from Luleå University of Technology, Sweden.
Ida Neldemo, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes pharmacometrics, pediatrics, and trial design in therapeutic areas such as oncology.
- Experience as temporary Consultant at Pharmetheus, Sweden, where she worked with hands-on application of pharmacometric approaches to support drug development.
- M.Sc in Pharmacy (2013) and Ph.D in Pharmaceutical Sciences (2019) from Uppsala University, Sweden.
Joakim Nyberg, Ph.D.
Principal Consultant & Team Leader
- Co-founded Pharmetheus in 2012, actively working in client projects, with continuous improvements, and managing the Enabler Team, including the subteams IT, Data Programming, and Technical Solutions.
- Expertise includes pharmacometrics, trial design, and systems development in therapeutic areas such as diabetes, oncology, and rare diseases.
- Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform pharmacometric research, primarily by supervision of Ph.D. students. Previously, he worked as System Developer at B&M Systemutveckling AB, Sweden.
- M.Sc. in Engineering Physics (2006) and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Marie Olsson
Administrative Assistant
- Joined Pharmetheus in 2019, providing administrative support.
- Experience as Administrative and Security Manager at City Gross Uppsala, Sweden, Store Manager at Willy:s Kungsgatan Uppsala, Sweden, and Manager of the perishable foods at Rätt Pris Uppsala, Sweden.
- Upper Secondary Diploma in Economics (1991) from Vilunda Gymnasium, Sweden.
Qing Xi Ooi, Ph.D.
Consultant
- Joined Pharmetheus in 2019, actively working in client projects.
- Expertise in pharmacometrics, quantitative systems pharmacology, and model-informed drug development.
- Experience as B.Pharm. course demonstrator and supervisor at the University of Otago, New Zealand, where she provided tutoring on pharmacokinetics and statistics as well as supervision on pharmacometrics projects. Previously, she worked as a clinical research scientist at the National Clinical Research Centre, Malaysia.
- M.Pharm. (2010) from the University of Manchester, UK, Ph.D. in Pharmacometrics (2018) from the University of Otago, New Zealand.
Sophie Peigné, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes clinical pharmacokinetics, pediatric drug development, in-vitro in-vivo correlation, and pharmacometrics in therapeutic areas such as oncology, immuno-oncology, cardiology, and neurology.
- Experience as PK Project Manager and Principal Pharmacometrician at Servier, France.
- Pharm.D. (2010), Master Degree in Pharmacokinetics (2010), and Ph.D. in Pharmacometrics (2015) from the University of Paris V, France.
Moriah Pellowe, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) and mathematical modeling, in particular cellular automata and systems biology, in therapeutic areas such as oncology.
- Experience as Postdoctoral Fellow at the University of Waterloo, Canada, where she developed a mechanistic inhalation model for drug disposition and an R-package for virtual bioequivalence testing to inform clinical trial design supported by a grant from the FDA, and as Sessional Lecturer at the University of Waterloo, Canada, where she taught undergraduate mathematics courses and a graduate PBPK course.
- B.Sc. in Mathematics (2014) from Redeemer University, Canada, and Ph.D. in Applied Mathematics (2019) from the University of Waterloo, Canada.
Arnaud Pharasyn, M.Sc.
Senior System Administrator & IT Manager
- Joined Pharmetheus in 2013, responsible for all IT systems and managing the IT operations team.
- Expertise includes system administration, systems development, and computerized system validation.
- Experience as Data Programmer at Pharmetheus, Research Engineer at the Swedish National Seismic Network, where he developed a software platform in the field of seismology, administrated and maintained the IT infrastructure and provided user support. Previously, he worked as IT Consultant at Eschelon AB, Sweden, Software Engineer at Mentor Graphics, France, Software Engineer at Ortho-Clinical Diagnostics, France, Consultant at Altran Technologies, France.
- M.Sc. in Physics (1996) from the Ecole Normale Supérieure de Lyon, France.
Elodie Plan, Ph.D.
Principal Consultant
- Co-founded Pharmetheus in 2012, actively working in client projects, leading the Communication Team, and providing management support in Pharmetheus activities.
- Expertise includes model informed drug development, pharmacometrics (especially count data models, Markov models, and item response theory models), and trial design in therapeutic areas such as neuroscience, women’s health, and immunology.
- Experience as Researcher at Uppsala University, where she has a part-time position to perform pharmacometric research, primarily by supervision of Postdoctoral Researchers. Previously, she worked as deputy CEO and Project Portfolio Team Leader at Pharmetheus, Sweden, and Visiting Scientist at Metrum Research Group, USA.
- M.Sc. in Biostatistics (2006) from University Paris Diderot, France, Pharm.D. (2007) from University of Poitiers, France, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Anna Pousette, B.Sc.
Contract Manager & Business Continuity Manager
- Joined Pharmetheus in 2020, managing customer contracts.
- Experience as Project Coordinator at BWN bygg AB, Sweden, where she was responsible for legal, financial, and fiscal aspects. Previously, she worked as Public Procurer at Region Uppsala, Sweden, Account Manager at Landauer Nordic AB, Sweden, Product Specialist ICU/Anesthesia and Nuclear Medicine at Covidien AB, Sweden, Customer Service at Tyco Healthcare AB, Sweden, Elementary School Teacher at Rudenschöldskolan, Sweden, Substitute Teacher at Lidköpings Kommun, Sweden, Sales Representative at AB DJ Stork, Sweden, Medical Interviewer at Lentus Research AB, Sweden, and Product Specialist Insulin Pumps/Anesthesia at Dartec AB, Sweden.
- B. Sc. in Management of Medical Technology (1996) from Stockholms Universitet, Sweden.
Peteris Prusis, Ph.D.
Data Programmer
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes data programming, molecular modelling, QSAR and systems development.
- Experience as Senior Research Scientist at Orion, Finland, where he performed computational chemistry and modeling support for drug discovery. Previously, he worked as Postdoctoral Researcher at AstraZeneca, Sweden, and Assistant Professor at Uppsala University, Sweden.
- M.Sc. in Bioorganic Chemistry (1990) from University of Latvia, Riga, and Ph.D. in Pharmaceutical Biosciences from Uppsala University, Sweden.
Miha Purg, Ph.D.
Associate System Administrator
- Joined Pharmetheus in 2021, administrating IT infrastructure, developing and validating tools, providing user support.
- Expertise includes system administration and systems development.
- Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he performed computational modeling of enzyme function, developed scientific software, designed and administered high performance computing environments.
- M.Sc. in Chemistry (2013) from University of Ljubljana, Slovenia, Ph.D. in Biochemistry (2018) from Uppsala University, Sweden.
Jakob Ribbing, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2014, actively working in client projects and serving as Deputy Project Portfolio Team Leader.
- Expertise includes model-informed drug development, model based meta analysis, and pediatrics in therapeutic areas such as allergy, inflammation, respiratory, neuroscience, and diabetes.
- Experience as Associate Director in Pharmacometrics at Pfizer in UK and Sweden, where he was responsible for team interaction and pharmacometrics deliveries for the Pfizer Allergy and Respiratory portfolio, as well as support to Pfizer global pharmacometrics and clinical pharmacology. Previously, he worked as Manager in Pharmacometrics at Pfizer INC, UK.
- M.Sc. in Pharmacy (2001) and Ph.D. in Biopharmaceutical Sciences (2007) from Uppsala University, Sweden.
Mikael Ringh, Ph.D.
Associate QC and Medical Writer
- Joined Pharmetheus in 2020, actively working in client projects, with continuous improvements, and providing medical writing support.
- Expertise includes quality control across therapeutic areas.
- Experience as Postdoctoral Researcher at Karolinska Institutet, Sweden and Pharmaceutical Manufacturing Assistant at GE Healthcare, Norway.
- M.Sc. in Medical Bioscience (2014) from Linköping University, Sweden, and Ph.D. in Medical Science (2019) from Karolinska Institutet, Sweden.
Daniel Röshammar, Ph.D.
Principal Consultant & Team Leader
- Joined Pharmetheus in 2018, actively working in client projects and as Project Portfolio Team Leader managing a team of MIDD Consultants.
- Expertise includes trial design, pediatrics, and regulatory advice in therapeutic areas such as cardiovascular diseases, infectious diseases, and oncology.
- Experience as Managing Director and Scientific Director at SGS Exprimo NV, Belgium, Senior Clinical Pharmacometrician and Section Director Clinical Pharmacometrics at AstraZeneca, Sweden, and Pharmacokineticist and Modeling and Simulation Specialist at Ferring Pharmaceuticals, Denmark.
- M.Sc. in Pharmaceutical Sciences (2003) from Uppsala University, Sweden, and Ph.D. in Medical Sciences (2009) from Gothenburg University, Sweden.
Eric Salgado, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes physiological based pharmacokinetic modeling (PBPK) and non-compartmental analysis in therapeutic areas such as oncology.
- Experience as Pharmacokinetics/Pharmacodynamics Postdoctoral Fellow at IQVIA and University of North Carolina, USA, where he supported hands-on pharmacometric projects such as population pharmacokinetics-pharmacodynamics modeling and simulation, non-compartmental analysis, and physiological based pharmacokinetic modeling including target-mediated drug disposition in the immuno-oncology setting.
- B.Sc. in Chemistry (2013) from the University of Georgia, USA and Ph.D. in Molecular & Systems Pharmacology (2018) from Emory University, USA.
Tomas Salmonson, Ph.D.
Board member
- Since 2022, a Pharmetheus Board Member
- Currently also a partner at Consilium Salmonson & Hemmings, Sweden.
- Experience as Senior Scientific Advisor, Director, and Head of Unit at the Medical Products Agency, Sweden. During that time, he also chaired the Committee for Medicinal Products for Human Use, CHMP, at the European Medicines Agency and before that he was a member of CHMP, representing Sweden.
- M.Sc. in Pharmacy (1986) and Ph.D. in Medicine (1990) from Uppsala University, Sweden.
Eric Sandström, M.Sc.
Associate Data Programmer & System Developer
- Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
- Expertise includes data programming and systems development.
- M.Sc. in Biotechnology Engineering (2019) from Uppsala University, Sweden.
Marie Sandström, Ph.D.
Chief Operations Officer
- Co-founded Pharmetheus in 2012, managing the Client Operations organization and supporting the Chief Executive Officer in leading the day to day operations of Pharmetheus.
- Expertise includes model informed drug development and clinical pharmacology in therapeutic areas such as neuroscience and oncology.
- Experience as Chief Executive Officer and Senior Consultant at Pharmetheus, where she managed the company and worked actively in client projects, providing clinical pharmacology advice and hands-on application of pharmacometric approaches to support drug development. Previously, she worked as Global Head of Clinical Pharmacometrics, Clinical Pharmacology & DMPK Projects Director Neuroscience, Head of Clinical Pharmacology Södertälje, and Clinical Project Pharmacometrician/Pharmacokineticist at AstraZeneca, Sweden, Lecturer and Associate Professor in Pharmacokinetics and Drug Therapy, Uppsala University, Sweden, and Pharmacist at Apoteksbolaget AB, Sweden.
- M.Sc. in Pharmacy (1989) and Ph.D. in Biopharmaceutical Sciences (2002) from Uppsala University, Sweden.
Céline Sarr, Ph.D.
Senior Consultant & Team Leader
- Joined Pharmetheus in 2016, actively working in client projects, leading the Client Operations Forum, and as Project Portfolio Team Leader managing a team of MIDD consultants.
- Expertise includes pharmacometrics, submission, pediatric investigation plans, and MIDD support in therapeutic areas such as oncology and metabolism disorders.
- Experience as Senior Consultant at SGS-Exprimo, Belgium, where she delivered modeling results to support submissions and internal decisions. Previously, she worked as Senior Expert Modeler at Novartis, Switzerland, Cluster Leader at Novartis, USA, and Modeler at Novartis, Switzerland.
- Pharm.D. (2004) from University Paris XII, France, and Ph.D. in Pharmaceutical Biosciences (2006) from University Lyon Claude Bernard, France.
Markus Seltmann
Associate System Administrator
- Joined Pharmetheus in 2018, administering and maintaining IT systems, providing user support.
- Expertise in system administration.
- Experience as Apprentice IT Specialist and Junior IT Specialist at ITMC, Technische Universität Dortmund, Germany, where he administered, maintained, and monitored databases, Linux servers and server-based applications.
- IT Specialist for System Integration (2017) from Robert-Bosch-Berufskolleg at Technische Universität Dortmund, Germany.
Prof. Ulrika Simonsson, Ph.D.
Advisor
- Co-founded Pharmetheus in 2012, advising in client projects.
- Expertise includes pharmacometrics and model informed drug development with extensive experience in regulatory interactions in therapeutic areas such as infectious diseases, cardiovascular diseases, diabetes, obesity, and cancer.
- Experience as Professor of Pharmacokinetics at Uppsala University, Sweden, where she supervises Ph.D. students in pharmacometrics and gives lectures. Previously, she worked as Senior Research Scientist at AstraZeneca R&D Mölndal, Sweden, Appointed Senior Lecturer and Director of Studies in Pharmacokinetics at Uppsala University, Sweden, Postdoctoral Researcher and Consultant at Pharsight Corporation, USA.
- M.Sc. in Pharmaceutical Sciences (1995) and Ph.D. in Pharmaceutical Biosciences (2000) from Uppsala University, Sweden.
Erik Sjögren, Assoc. Prof, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2017, actively working in client projects.
- Expertise includes physiological based pharmacokinetic and biopharmaceutics modeling and simulation, clinical pharmacology, and pediatrics across therapeutic areas.
- Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform research and supervise Ph.D. students. Previously, he worked as Acting Senior Lecturer at Uppsala University, Sweden and Postdoctoral Researcher at AstraZeneca Mölndal, Sweden.
- M.Sc. in Pharmaceutical Sciences (2004), Ph.D. in Pharmaceutical Sciences (2010), Associate Professor in Biopharmaceutics (2016) from Uppsala University, Sweden.
Giovanni Smania, Ph.D.
Senior Consultant
- Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and serving as Deputy Project Portfolio Team Leader.
- Expertise includes pharmacometrics (especially translational models, model informed precision dosing and covariate analysis), model informed drug development and in-vitro in-vivo correlation in therapeutic areas such as oncology, neuroscience, and hematology.
- Experience as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, where he supported early clinical development of products in oncology. Previously, he worked as Collaborator and Research Fellow at CVBF, Italy.
- M.Sc. in Bioengineering (2013) and Ph.D. in Bioengineering and Bioinformatics (2017) from University of Pavia, Italy.
Lénaïg Tanneau, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2022, actively working in client projects.
- Expertise includes QTc modeling and pharmacometrics in therapeutic areas such as infectious diseases and oncology.
- Experience as pharmacometrician at Ipsen, France, as contract researcher at Uppsala University in collaboration with Merck KGaA, and as temporary MIDD Consultant at Pharmetheus, Sweden.
- M.Sc. in Pharmacokinetics (2014) from Paris Descartes University, France, Pharm.D. (2015) from University of Nantes, France, and Ph.D. in Pharmacometrics (2022) from Uppsala University, Sweden.
Sami Ullah, Ph.D.
Associate Consultant
- Joined Pharmetheus in 2021, actively working in client projects.
- Expertise includes clinical pharmacology and population pharmacokinetic modeling and simulation of antimicrobial agents in tissues and body fluids.
- Experience as Hospital Pharmacist at PAEC General Hospital, Pakistan and as Lecturer at the Abasyn University Peshawar, Pakistan.
- Pharm.D. (2010) from Gomal University, Pakistan, and Ph.D. in Pharmacy (2020) from University of Bonn, Germany.
Monique Wouters, M.Sc.
Senior QC and Medical Writer
- Started working for Pharmetheus as a subcontractor in 2013, actively working in client projects, with continuous improvements, and training Pharmetheus colleagues in quality control.
- Expertise includes medical writing, quality control, and method development for quality control review of pharmacometric projects across therapeutic areas.
- Experience as Independent Consultant at W&D Consulting bvba, Belgium, where she provided services in clinical pharmacokinetics, medical writing, quality control, and process improvement. Previously, she worked as Global Phase I-IIa Biometrics Manager, Data Review Coordinator, Project Manager Biometrics, and Clinical Data Reviewer at SGS LSS, Belgium, Specialist Clinical Pharmacokinetics at Johnson & Johnson PRD, Belgium, Clinical Data Reviewer at Janssen Research Foundation, Belgium, Marketing positions at Ciba-Geigy, Belgium, and as Administrative and Scientific Assistant at Centraal Laboratorium, Antwerp, Belgium.