Pharmetheus at PAGE 2022

Scientific contributions

Posters and talks with Pharmetheus affiliation

Marblellous donations

Thank you for participating in our marblellous donation event at our exhibition booth at Page 2022! By choosing which of the four selected worthwhile causes was closest to your heart, you’ve been assisting us in determining the distribution of how our entire give-away fund is being given away. The votes have been compiled and we will make donations accordingly.


Education in pharmacometrics regardless of socio-economic background:
Uppsala Pharmacometrics Summer School
28%


Reliable knowledge – a solid ground for informed decisions:
Gapminder

23%


Cancer treatment, research, and education:
Gustave Roussy
20%


• Protect the forests – preserve the environment by planting trees:
Planète Urgence
29%


Team

Pharmetheus’ delegation (22) for PAGE 2022

Anaïs Glatard

Anaïs Glatard, Ph.D.

Consultant
  • Joined Pharmetheus in 2020, actively working in client projects.
  • Expertise includes clinical pharmacology and pharmacometrics in therapeutic areas such as neuroscience.
  • M.Sc. in Pharmacology and modeling, Pharm.D. (2014) from University of Lyon 1, France, and Ph.D. in Life Sciences (2019) from University of Lausanne, Switzerland.

Andrea Henrich, Ph.D.

Consultant
  • Joined Pharmetheus in 2020, actively working in client projects.
  • Expertise includes QTc analysis, drug-drug interactions, and trial design in therapeutic areas such as oncology, cardiovascular, and immunology.
  • Experience as Modeling and Simulation Scientist at Idorsia Pharmaceuticals, Switzerland, where she performed population pharmacokinetic-pharmacodynamic analyses and concentration-QT modeling in different therapeutic areas.
  • Pharmacist (2013) from Johann-Wolfgang-Goethe-University, Germany, and Ph.D. in Clinical Pharmacy (2020) from Freie Universitaet Berlin, Germany.
Arnaud Gaby

Arnaud Gaby, B.Sc.

Senior Data Programmer & Team Leader
  • Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and managing the team of Data Programmers.
  • Expertise includes systems development and data programming in therapeutic areas such as neuroscience, ophtalmology, immunology, respiratory and oncology.
  • Experience as Principal Statistical Programmer in Pharmacometrics at Novartis Pharma, Switzerland, where he prepared modeling datasets for pharmacokinetic-pharmacodynamic analyses and integrated study data from phase I to IV across indications and using different data standards. Previously, he worked as SAS Programmer at the Institut de Recherche Pierre-Fabre, France, and Biostatistician at Aventis Pasteur, France and bioMérieux, France.
  • B.Sc. in Statistics and Computing (1997) from the University of the West of England, UK.
Celine Sarr

Céline Sarr, Ph.D.

Senior Consultant & Team Leader
  • Joined Pharmetheus in 2016, actively working in client projects, leading the Client Operations Forum, and as Project Portfolio Team Leader managing a team of MIDD consultants.
  • Expertise includes pharmacometrics, submission, pediatric investigation plans, and MIDD support in therapeutic areas such as oncology and metabolism disorders.
  • Experience as Senior Consultant at SGS-Exprimo, Belgium, where she delivered modeling results to support submissions and internal decisions. Previously, she worked as Senior Expert Modeler at Novartis, Switzerland, Cluster Leader at Novartis, USA, and Modeler at Novartis, Switzerland.
  • Pharm.D. (2004) from University Paris XII, France, and Ph.D. in Pharmaceutical Biosciences (2006) from University Lyon Claude Bernard, France.
Chayan Acharya

Chayan Acharya, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2015, actively working in client projects, with continuous improvements, and training Pharmetheus colleagues in R.
  • Expertise includes model informed drug development, non-compartmental analysis, and pharmacometrics in therapeutic areas such as immunology, inflammation and analgesia.
  • Experience as Postdoctoral Researcher at Uppsala University, Sweden, where he developed an R-package for population pharmacokinetic model diagnosis using non-compartmental analysis metrics, and as Postdoctoral Fellow at University of California San Diego, USA and University of Bordeaux 1, France, with molecular force field development and structure/ligand-based drug design.
  • M.Sc. in Physics (2003) from the Indian Institute of Technology Bombay, India, and Ph.D. in Pharmaceutical Sciences (2009) from University of Maryland Baltimore, USA.

Elodie Plan, Ph.D.

Principal Consultant & Team Leader
  • Co-founded Pharmetheus in 2012, actively working in client projects, leading the Business Development Team and the Communication & Marketing Team, and providing management support in Pharmetheus activities.
  • Expertise includes model informed drug development, pharmacometrics (especially count data models, Markov models, and item response theory models), and trial design in therapeutic areas such as neuroscience, women’s health, and immunology.
  • Experience as Researcher at Uppsala University, where she has a part-time position to perform pharmacometric research, primarily by supervision of Postdoctoral Researchers. Previously, she worked as deputy CEO and Project Portfolio Team Leader at Pharmetheus, Sweden, and Visiting Scientist at Metrum Research Group, USA.
  • M.Sc. in Biostatistics (2006) from University Paris Diderot, France, Pharm.D. (2007) from University of Poitiers, France, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Enrica Mezzalana

Enrica Mezzalana, Ph.D.

Consultant
  • Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
  • Expertise includes pharmacometrics (especially time-to-event models and target-mediated drug disposition models) and physiological based pharmacokinetic modeling (PBPK, mainly for drug-drug interactions) in therapeutic areas such as oncology, pain, and diabetes.
  • Experience as Modeling and Simulation Scientist at SGS Exprimo NV, Belgium, where she developed, interpreted, and reported population pharmacokinetic-pharmacodynamic models, optimal design, and physiological based pharmacokinetic modeling for drug-drug interaction predictions. Previously, she worked as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, and as Postdoctoral Research Fellow at University of Pavia, Italy.
  • M.Sc. in Bioengineering (2010) from the University of Padova, Italy, and Ph.D. in Bioengineering and Bioinformatics (2014) from University of Pavia, Italy.
Erik Sjögren

Erik Sjögren, Assoc. Prof, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2017, actively working in client projects.
  • Expertise includes physiological based pharmacokinetic and biopharmaceutics modeling and simulation, clinical pharmacology, and pediatrics across therapeutic areas.
  • Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform research and supervise Ph.D. students. Previously, he worked as Acting Senior Lecturer at Uppsala University, Sweden and Postdoctoral Researcher at AstraZeneca Mölndal, Sweden.
  • M.Sc. in Pharmaceutical Sciences (2004), Ph.D. in Pharmaceutical Sciences (2010), Associate Professor in Biopharmaceutics (2016) from Uppsala University, Sweden.
Fanny Gallais

Fanny Gallais, Ph.D.

Consultant
  • Joined Pharmetheus in 2020, actively working in client projects.
  • Expertise includes pharmacometrics within oncology.
  • M.Sc. in Bioengineering and Bioinformatics (2017) from National Institute of Applied Sciences of Lyon, France, M.Sc. in Pharmacology and Modeling (2017) from University of Lyon 1, France, and Ph.D. in Pharmacometrics (2020) from the University of Toulouse III Paul Sabatier, France.

Giovanni Smania, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2018, actively working in client projects, with continuous improvements, and serving as Deputy Project Portfolio Team Leader.
  • Expertise includes pharmacometrics (especially translational models, model informed precision dosing and covariate analysis), model informed drug development and in-vitro in-vivo correlation in therapeutic areas such as oncology, neuroscience, and hematology.
  • Experience as Clinical Pharmacology and Pharmacometrics Specialist at Menarini Ricerche, Italy, where he supported early clinical development of products in oncology. Previously, he worked as Collaborator and Research Fellow at CVBF, Italy.
  • M.Sc. in Bioengineering (2013) and Ph.D. in Bioengineering and Bioinformatics (2017) from University of Pavia, Italy.
Joakim Nyberg

Joakim Nyberg, Ph.D.

Principal Consultant & Team Leader
  • Co-founded Pharmetheus in 2012, actively working in client projects, with continuous improvements, and managing the Enabler Team, including the subteams IT, Data Programming, and Technical Solutions.
  • Expertise includes pharmacometrics, trial design, and systems development in therapeutic areas such as diabetes, oncology, and rare diseases.
  • Experience as Researcher at Uppsala University, Sweden, where he has a part-time position to perform pharmacometric research, primarily by supervision of Ph.D. students. Previously, he worked as System Developer at B&M Systemutveckling AB, Sweden.
  • M.Sc. in Engineering Physics (2006) and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Jurgen Langenhorst

Jurgen Langenhorst, Ph.D.

Consultant
  • Joined Pharmetheus in 2019, actively working in client projects.
  • Expertise includes pediatrics, QTc analysis, and clinical pharmacology in therapeutic areas such as immunology and oncology.
  • Experience as Production Pharmacist at the University Medical Center Utrecht, the Netherlands where he supported daily practise in the manufacturing department of the pharmacy.
  • M.Sc. in Pharmacy (2015) from Utrecht University, the Netherlands and Ph.D. in Pharmaceutics (2019) from the University Medical Centre Utrecht, the Netherlands.
Maddlie Bardol

Maddlie Bardol, Ph.D.

Associate Consultant
  • Joined Pharmetheus in 2021, actively working in client projects.
  • Expertise includes pharmacometrics and pediatrics in therapeutic areas such as pain management and sedation.
  • M.Sc. in Pharmacometrics (2017) and Pharm.D. (2019) from Paris Descartes University, France, and Ph.D. in Pharmacometrics (2021) from University College London, UK.
Marcus Björnsson

Marcus Björnsson, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2014, actively working in client projects and serving as Deputy Project Portfolio Team Leader.
  • Expertise includes pediatrics and non-compartmental analysis in therapeutic areas such as neuroscience and orphan indications.
  • Experience as Neuroscience Therapy Area Pharmacometrics Expert at AstraZeneca R&D, Sweden, where he had strategic and scientific accountability for pharmacometric activities within the neuroscience therapy area. Previously, he worked as Clinical Pharmacokineticist, Senior Research Scientist, and Senior Pharmacometrician at AstraZeneca R&D, Sweden, and Research Scientist at Astra Pain Control, Sweden.
  • M.Sc. in Pharmaceutical Sciences (1999) and Ph.D. in Pharmacokinetics and Drug Therapy (2013) from Uppsala University, Sweden.
Martin Bergstrand

Martin Bergstrand, Ph.D.

Principal Consultant
  • Co-founded Pharmetheus in 2012, actively working in client projects and with continuous improvements.
  • Expertise includes trial design, pharmacometrics (especially complex pharmacokinetics, mechanism based PKPD and Markov models), and model informed drug development in therapeutic areas such as infectious, metabolic, and cardiovascular diseases.
  • Experience as part-time Researcher at Uppsala University, Sweden, where he performed pharmacometric research primarily by supervision of Ph.D. students. Previously, he worked as Visiting Scientist at Mahidol-Oxford Tropical Medicine Research Unit, Thailand, and Clinical Pharmacology Scientist at AstraZeneca R&D Mölndal, Sweden.
  • M.Sc. in Biomedicine (2003) from University of Kalmar, Sweden, and Ph.D. in Pharmaceutical Biosciences (2011) from Uppsala University, Sweden.
Marylore Chenel

Marylore Chenel, Ph.D.

Principal Consultant & Team Leader
  • Joined Pharmetheus in 2021, actively working in client projects, with continuous improvements, and as Project Portfolio Team Leader managing a team of MIDD consultants.
  • Expertise includes model-informed drug development, clinical pharmacology and regulatory advices in therapeutic areas such as oncology/immuno-oncology, immuno-inflammation, cardiology, and diabetes.
  • Experience as Head of Global Pharmacometrics and Clinical Pharmacokinetics at Servier, France, where she led a team supporting the drug development portfolio from research to submission including lifecycle management. Previously, she served as Head and Deputy Head of Clinical Pharmacometrics and Clinical Pharmacokinetics, and as a Pharmacometrician at Servier, France, and as Postdoctoral Fellow at the University of Manchester, UK.
  • PharmD (2000) and M.Sc. in Pharmacokinetics (2000) from the University of Paris V, France, and Ph.D in Pharmacokinetics – PKPD modeling from the University of Poitiers, France.
Moustafa Ibrahim

Moustafa Ibrahim, Ph.D.

Consultant
  • Joined Pharmetheus in 2019, actively working in client projects.
  • Expertise includes trial design, clinical pharmacology, model informed drug development, and pharmacometrics in therapeutic areas such as hematology, immunology, diabetes, pediatrics, and neurosciences.
  • M.Sc. in Clinical Pharmacy (2012) from Helwan University, Egypt, and Ph.D. in Pharmaceutical Biosciences (2019) from Uppsala University, Sweden.
Niclas Jonsson

Niclas Jonsson, Ph.D.

Principal Consultant
  • Joined Pharmetheus in 2013, actively working in client projects, leading the Continuous Improvement Team, and serving as Project Harmonization Manager.
  • Expertise includes pharmacometrics and its applications across therapeutic areas.
  • Experience as Senior Consultant at Exprimo NV, Sweden, where he interacted with clients and provided pharmacokinetic, pharmacodynamic, and disease modeling and simulation services to drug development programs in various therapeutic areas. Previously, he worked as Global Head of Modeling and Simulation at Hoffman-La Roche, Switzerland, Associate Professor of Applied Pharmacometrics and Senior Lecturer at Uppsala University, and as Postdoctoral Researcher at University of California San Francisco, USA. Co-developer of the software programs Xpose 4 and PsN
  • M.Sc. in Pharmacy (1991) and Ph.D. in Biopharmaceutical Sciences (1998) from Uppsala University, Sweden.
Per Lundström

Per Lundström, B.Sc.

Communication & Marketing Coordinator
  • Joined Pharmetheus in 2018, providing Communication & Marketing coordination.
  • Experience in communication, marketing, commercial photography, graphical design and administration. Previously working in the Business Operations Team at Pharmetheus, providing administration support and managing customer contracts.
  • B.Sc. in Behavioral Sciences (2018) from Uppsala University, Sweden.
Qing Xi Ooi

Qing Xi Ooi, Ph.D.

Consultant
  • Joined Pharmetheus in 2019, actively working in client projects.
  • Expertise in pharmacometrics, quantitative systems pharmacology, and model-informed drug development.
  • Experience as B.Pharm. course demonstrator and supervisor at the University of Otago, New Zealand, where she provided tutoring on pharmacokinetics and statistics as well as supervision on pharmacometrics projects. Previously, she worked as a clinical research scientist at the National Clinical Research Centre, Malaysia.
  • M.Pharm. (2010) from the University of Manchester, UK, Ph.D. in Pharmacometrics (2018) from the University of Otago, New Zealand.
Siv Jönsson

Siv Jönsson, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2019, actively working in client projects and with continuous improvements.
  • Expertise includes pharmacometrics, regulatory advice, and pediatric drug development, in hemophilia and across therapeutic areas.
  • Experience as Researcher at Uppsala University, Sweden, where she has a part-time position to perform pharmacometric research, primarlily by supervision of Ph.D. students. Previously, she worked as Senior Lecturer and Researcher at Uppsala University, Sweden, Pharmacokinetic Assessor at the Medical Products Agency, Sweden, Senior Research Scientist and Pharmacometrician at AstraZeneca, Sweden, Pharmacokineticist at Kabi Pharma and Kabi Pharmacia, Sweden, and Pharmacist at the Swedish Poison Information Centre, Sweden.
  • M.Sc. in Pharmacy (1988) and Ph.D. in Pharmacokinetics and Drug Therapy (2004) from Uppsala University, Sweden.
Tobias Kanacher

Tobias Kanacher, Ph.D.

Senior Consultant
  • Joined Pharmetheus in 2019, actively working in client projects.
  • Expertise includes physiological based pharmacokinetic modeling (PBPK), pediatrics, and MIDD in therapeutic areas such as oncology, women’s health, and cardiovascular diseases.
  • Experience as Consultant Modeling and Simulation at SGS Exprimo NV, Belgium, where he provided advice and hands-on application of pharmacometric approaches to support drug development in various therapeutic areas. Previously, he worked as Systems Pharmacology Expert at Bayer / Bayer Technology Services GmbH, Germany, PBPK Expert in Exploratory ADME at Nycomed: a Takeda Company, Germany, Laboratory Team Leader in Exploratory ADME at Altana Pharma AG / Nycomed Gmbh, Germany, and Laboratory Team and Target-Project Leader in Preclinical Research at Altana Pharma AG, Germany.
  • Pharmacist Licensure (1999) from the University Marburg, Germany, and Ph.D. in Pharmaceutical Biochemistry (2003) from the University Tübingen, Germany.