Our engagement in PBPK-QSP takes many forms! We’ve recently kicked off three new research projects, about i) an infrastructure for streamlining processes of PBPK projects, ii) a framework for evaluating the performance of PBPK models, and ii) PBPK-based prediction of gastric pH-dependent DDIs for weak base drugs.
In order to support Pharmetheus in this, we’re welcoming Master students Yasmine Sundelin, Dylan Garamani, and Samar Salem, under the supervision of Erik Sjögren and Tobias Kanacher.
These initiatives, just like the SubQ platform, ultimately support our PBPK-QSP services to our clients throughout the phases in drug discovery and development, covering, among many aspects, drug–drug interactions and pediatric predictions.