Forest plots can be used to efficiently summarize the impact of covariates and other predictors on the primary and secondary parameters from population pharmacokinetic and pharmacodynamic models. They can also be used to illustrate the outcome in important patient subgroups and relate the outcome to observed or hypothetical reference subjects. Forest plots are recommended by regulatory authorities and are becoming a standard component of submission packages to the FDA and other regulatory agencies.
The goals of the workshop are:
After the workshop, participants will be able to understand Forest plots and will be aware of the various assumptions that may influence how Forest plots can be interpreted. The participants will also be familiar with the creation of Forest plots in R using modeling output NONMEM, PsN or R.
Participants are expected to use their own laptops and have R and Rstudio installed. Example data and training R code will be provided at the workshop.